Ladybird Homeobox 1 Peptide 2


Background

Catalog Number:

CPTC-LBX1-2

Target Antigen:

Ladybird Homeobox 1 Peptide 2

Isotype:

IgG

Species:

Rabbit Monoclonal Antibody

Last Updated:

09/24/2020

Antigen Recognition(s):

Peptide

Thematic Panel(s):

Epithelial Mesenchymal Transition (EMT)

SOP:

Publications
Characterization Data [Compare Characterization Data]
  IHC HPA
Download This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org) (339.7 KB)

CPTC-LBX1-2 Evaluation by the Human Protein Atlas

Result: Negative

This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org)


Background

Catalog Number:

CPTC-LBX1-3

Target Antigen:

Ladybird Homeobox 1 Peptide 2

Isotype:

IgG

Species:

Rabbit Monoclonal Antibody

Last Updated:

09/24/2020

Antigen Recognition(s):

Peptide

Thematic Panel(s):

Epithelial Mesenchymal Transition (EMT)

SOP:

Publications
Characterization Data [Compare Characterization Data]
  IHC HPA
Download This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org) (339.5 KB)

CPTC-LBX1-3 Evaluation by the Human Protein Atlas

Result: Negative

This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org)


Background

NCI Identification Number:

00076

Antigen Name:

Ladybird Homeobox 1 Peptide 2

CPTC Name:

CPTC-LBX1 Peptide 2

Keywords:

LBX1H; Ladybird Homeobox Protein Homolog 1; Ladybird Homeobox Homolog 1 (Drosophila); HPX-6; HPX6; homeobox; Lady Bird-Like Homeobox; Ladybird Homeobox Homolog 1; Transcription Factor LBX1; transcription Factor Similar To D. Melanogaster Homeodomain Protein Lady Bird Late

Function:

This gene and the orthologous mouse gene were found by their homology to the Drosophila lady bird early and late homeobox genes. In the mouse, this gene is a key regulator of muscle precursor cell migration and is required for the acquisition of dorsal identities of forelimb muscles.

LBX1 (ladybird homeobox 1) is a protein-coding gene. Diseases associated with LBX1 include leri weill dyschondrosteosis, and adenoid cystic carcinoma. GO annotations related to this gene include transcription regulatory region sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is DLX2.

Transcription factor required for the development of GABAergic interneurons in the dorsal horn of the spinal cord and migration and further development of hypaxial muscle precursor cells for limb muscles, diaphragm and hypoglossal cord

Chromosomal Localization:

10q24

NCBI Accession Number:

NP_006553.2

UniProt Accession Number:

P52954

DNA Source:

The NCI acknowledges the generous advice and gene clones provided by Robert A. Weinberg at the Ludwig Center for Cancer Research of the Massachusetts Institute of Technology. These reagents have been provided by the Division of Cancer Treatment and Diagnosis (DCTD) of the National Cancer Institute (NCI) using funding of the American Recovery and Reinvestment Act of 2009

Immunogen:

Synthetic Peptide

Vector Name:

N/A

Extinction Coefficient:

Buffers:

Expressed Sequence:

cLEELASKTFKGLEVSVLQA

Native Sequence:

Calculated Isoelectric Point:

0

Molecular Weight:

2200

Last Updated:

09/16/2019

Links

Characterization Data

SOPs

No SOPs available.

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