Background
Catalog Number:
CPTC-S100A7-1
Target Antigen:
S100 Calcium Binding Protein A7 Peptide 1
Isotype:
IgG
Species:
Rabbit Recombinant Cloned Antibody
Last Updated:
08/23/2022
Antigen Recognition(s):
Peptide
Characterization Data [Compare Characterization Data]
IHC HPA
Download This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org) (346.9 KB)
CPTC-S100A7-1 Evaluation by the Human Protein Atlas
Result: Negative
This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org)
Characterization SOP Files
Immuno-MRM
CPTC-S100A7-1 iMRM
Result: Positive
iMRM data obtain using antibody CPTC-S100A7-1 to immuno-precipitate peptide GTNYLADVFEK (CPTC-S100A7 Peptide 1)
Data provided by the Carr Lab, Broad Institute
https://www.broadinstitute.org/proteomics/protocols
Characterization SOP Files
Western Blot - Recombinant Protein or Peptide
CPTC-S100A7-1 Recombinant Protein WB
Result: Negative
Automated Western Blot with recombinant S100A7 protein
Characterization SOP Files
Background
NCI Identification Number:
00333
Antigen Name:
S100 Calcium Binding Protein A7 Peptide 1
CPTC Name:
CPTC-S100A7 Peptide 1
Aliases:
S100 Calcium Binding Protein A7; Protein S100-A7; S100A7c; PSOR1; S100 Calcium-Binding Protein A7 (Psoriasin 1); S100 Calcium Binding Protein A7 (Psoriasin 1); S100 Calcium-Binding Protein A7; Psoriasin 1; Psoriasin; S100A7C; S100A7
Function:
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities.S100A7 (S100 Calcium Binding Protein A7) is a Protein Coding gene. Diseases associated with S100A7 include Bladder Squamous Cell Carcinoma and Anal Fistula. Among its related pathways are Validated targets of C-MYC transcriptional repression and Innate Immune System. Gene Ontology (GO) annotations related to this gene include calcium ion binding and RAGE receptor binding. An important paralog of this gene is S100A7A.
Chromosomal Localization:
1q21.3
Accession Number:
NP_002954.2
UniProt Accession Number:
P31151
DNA Source:
N/A
Immunogen:
Synthetic Peptide
Vector Name:
N/A
Extinction Coefficient:
Buffers:
Expressed Sequence:
GTNYLADVFEK
Native Sequence:
Calculated Isoelectric Point:
Molecular Weight:
1210
Last Updated:
08/23/2020
Links
- CPTAC Assay Portal - EnsEMBL S100A7
- CPTAC Assay Portal - Entrez S100A7
- Uniprot - Uniprot P31151
Characterization Data
SOPs
No SOPs available.
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