Jun Proto-Oncogene Peptide 1


Background

Catalog Number:

CPTC-JUN-1

RRID:

AB_2722070

Target Antigen:

Jun Proto-Oncogene Peptide 1

Isotype:

IgG1

Species:

Mouse Monoclonal Antibody

Last Updated:

08/23/2022

Antigen Recognition(s):

Peptide, Phosphorylation

Thematic Panel(s):

DNA Damage Response (DDR) Pathway

Purchase
Characterization Data [Compare Characterization Data]
  IHC HPA
Download This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org) (329.9 KB)

CPTC-JUN-1 Evaluation by the Human Protein Atlas

Result: Negative

This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org)


  IP
Click to enlarge image Immuno-Precipitation Mass Spectrometry using CPTC-JUN-1 antibody with CPTC-JUN proto-Oncogene peptide 1 (phosphorylated) as the target antigen. Click image to enlarge

CPTC-JUN-1 phospho IPMS

Result: Positive

Immuno-Precipitation Mass Spectrometry using CPTC-JUN-1 antibody with CPTC-JUN proto-Oncogene peptide 1 (phosphorylated) as the target antigen.


  IP
Click to enlarge image Immuno-Precipitation Mass Spectrometry using CPTC-JUN-1 antibody with CPTC-JUN proto-Oncogene peptide 1 (non-phosphorylated) as the target antigen. Click image to enlarge

CPTC-JUN-1 non-phosho IPMS

Result: Positive

Immuno-Precipitation Mass Spectrometry using CPTC-JUN-1 antibody with CPTC-JUN proto-Oncogene peptide 1 (non-phosphorylated) as the target antigen.


Background

Catalog Number:

CPTC-JUN-2

RRID:

AB_2722071

Target Antigen:

Jun Proto-Oncogene Peptide 1

Isotype:

IgG1

Species:

Mouse Monoclonal Antibody

Last Updated:

01/03/2024

Antigen Recognition(s):

Peptide, Phosphorylation

Thematic Panel(s):

DNA Damage Response (DDR) Pathway

Purchase
External Links
Characterization Data [Compare Characterization Data]
  IHC HPA
Download This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org) (146.9 KB)

CPTC-JUN-2 Evaluation by the Human Protein Atlas

Result: Positive

This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org)


  IP
Click to enlarge image Immuno-Precipitation Mass Spectrometry using CPTC-JUN-2 antibody with CPTC-JUN proto-Oncogene peptide 1 (phosphorylated) as the target antigen. Click image to enlarge

CPTC-JUN-2 phospho IPMS

Result: Positive

Immuno-Precipitation Mass Spectrometry using CPTC-JUN-2 antibody with CPTC-JUN proto-Oncogene peptide 1 (phosphorylated) as the target antigen.


  IP

CPTC-JUN-2 non-phsopho IPMS

Result: Negative

CPCT-JUN-2 did not react with non-phosphorylated peptide


Background

Catalog Number:

CPTC-JUN-3

RRID:

AB_2722072

Target Antigen:

Jun Proto-Oncogene Peptide 1

Isotype:

IgG1

Species:

Mouse Monoclonal Antibody

Last Updated:

08/23/2022

Antigen Recognition(s):

Peptide, Phosphorylation

Thematic Panel(s):

DNA Damage Response (DDR) Pathway

Purchase
Characterization Data [Compare Characterization Data]
  IHC HPA
Download This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org) (310.6 KB)

CPTC-JUN-3 Evaluation by the Human Protein Atlas

Result: Negative

This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org)


  IP
Click to enlarge image Immuno-Precipitation Mass Spectrometry using CPTC-JUN-3 antibody with CPTC-JUN proto-Oncogene peptide 1 (phosphorylated) as the target antigen. Click image to enlarge

CPTC-JUN-3 phospho IPMS

Result: Positive

Immuno-Precipitation Mass Spectrometry using CPTC-JUN-3 antibody with CPTC-JUN proto-Oncogene peptide 1 (phosphorylated) as the target antigen.


  IP

CPTC-JUN-3 non-phsopho IPMS

Result: Negative

CPTC-JUN-3 did not react with the non-phosphorylated peptide


Background

Catalog Number:

CPTC-JUN-4

RRID:

AB_2877660

Target Antigen:

Jun Proto-Oncogene Peptide 1

Isotype:

IgG

Species:

Rabbit Monoclonal Antibody

Last Updated:

03/20/2024

Antigen Recognition(s):

Peptide, Endogenous, Phosphorylation

Thematic Panel(s):

DNA Damage Response (DDR) Pathway

External Links
Purchase
Publications
Characterization Data [Compare Characterization Data]
  IHC HPA
Download This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org) (320.9 KB)

CPTC-JUN-4 Evaluation by the Human Protein Atlas

Result: Negative

This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org)


  Immuno-MRM
Click to enlarge image Immuno-MRM chromatogram of CPTC-JUN-4 antibody (see CPTAC assay portal for details: https://assays.cancer.gov/CPTAC-3233) 

Data provided by the Paulovich Lab, Fred Hutch (https://research.fredhutch.org/paulovich/en.html) Click image to enlarge

CPTC-JUN-4 iMRM

Result: Positive

Immuno-MRM chromatogram of CPTC-JUN-4 antibody (see CPTAC assay portal for details: https://assays.cancer.gov/CPTAC-3233)

Data provided by the Paulovich Lab, Fred Hutch (https://research.fredhutch.org/paulovich/en.html)


  Immuno-MRM
Click to enlarge image Immuno-MRM chromatogram of CPTC-JUN-4 antibody (see CPTAC assay portal for details: https://assays.cancer.gov/CPTAC-3232 for non-phosphorylated peptide and https://assays.cancer.gov/CPTAC-3233  for phosphorylated peptide)
Data provided by the Paulovich Lab, Fred Hutch (https://research.fredhutch.org/paulovich/en.html). Data shown were obtained from cell lysate. Click image to enlarge

CPTC-JUN-4 iMRM

Result: Positive

Immuno-MRM chromatogram of CPTC-JUN-4 antibody (see CPTAC assay portal for details: https://assays.cancer.gov/CPTAC-3232 for non-phosphorylated peptide and https://assays.cancer.gov/CPTAC-3233 for phosphorylated peptide)
Data provided by the Paulovich Lab, Fred Hutch (https://research.fredhutch.org/paulovich/en.html). Data shown were obtained from cell lysate.


Background

NCI Identification Number:

00097

Antigen Name:

Jun Proto-Oncogene Peptide 1

CPTC Name:

CPTC-JUN Peptide 1

Aliases:

V-Jun Avian Sarcoma Virus 17 Oncogene Homolog; JUN oncogene; Activator Protein 1; Proto-Oncogene C-Jun; AP1; p39; V-Jun Sarcoma Virus 17 Oncogene Homolog; AP-1; c-JUN; Enhancer-Binding Protein AP1; Jun Activation Domain Binding Protein; Transcription Factot AP-1

Function:

This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.

JUN (jun proto-oncogene) is a protein-coding gene. Diseases associated with JUN include sarcoma, and campylobacteriosis. GO annotations related to this gene include transcription coactivator activity and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is JUND.

Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.

Chromosomal Localization:

1p32-p31

Accession Number:

NP_002219.1

UniProt Accession Number:

P05412

DNA Source:

N/A

Immunogen:

Synthetic Peptide

Vector Name:

N/A

Extinction Coefficient:

Buffers:

Expressed Sequence:

NSDLLT(pS)PDVGLLK (pS63)

Native Sequence:

Calculated Isoelectric Point:

0

Molecular Weight:

1540

Last Updated:

03/11/2015

Links

Characterization Data

SOPs

No SOPs available.

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