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TNF Receptor Superfamily Member 9 Peptide 1

Antibody: CPTC-TNFRSF9-4
Background

Catalog Number:

CPTC-TNFRSF9-4

Target Antigen:

TNF Receptor Superfamily Member 9 Peptide 1

Isotype:

IgG2b

Species:

Mouse Monoclonal Antibody

Last Updated:

02/09/2024

Antigen Recognition(s):

Peptide

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Characterization Data [Compare Characterization Data]
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Antibody: CPTC-TNFRSF9-5
Background

Catalog Number:

CPTC-TNFRSF9-5

Target Antigen:

TNF Receptor Superfamily Member 9 Peptide 1

Isotype:

IgG1

Species:

Mouse Monoclonal Antibody

Last Updated:

02/09/2024

Antigen Recognition(s):

Peptide

Thematic Panel(s):

Immuno-Oncology (IO)

External Links
Purchase
Publications
Characterization Data [Compare Characterization Data]
  NCI 60 Protein Array

CPTC-TNFRSF9-5 Protein Array

Result: Negative

This antibody is not suitable for use in a Reverse Phase Protein Array format as described in SOP M-105.


Characterization SOP Files

  Western Blot - Recombinant Protein or Peptide

CPTC-TNFRSF9-5 Western Blot Recombinant Protein

Result: Negative

Western blot using CPTC-TNFRSF9-5 as primary antibody against human tumor necrosis factor receptor superfamily, member 9 (TNFRSF9) recombinant protein (lane 2). Expected molecular weight - 20.0 kDa. Molecular weight standards are also included (lane 1).


Characterization SOP Files

  Western Blot - Tissue or Cell Lysate
Click to enlarge image Western blot using CPTC-TNFRSF9-5 as primary antibody against A549 (lane 2), HeLa (lane 3), Jurkat (lane 4), MCF7 (lane 5), H226 (lane 6), and PBMC (lane 7) whole cell lysates. Expected molecular weight - 27.9 kDa. Molecular weight standards are also included (lane 1). Click image to enlarge

CPTC-TNFRSF9-5 Western Blot

Result: Negative

Western blot using CPTC-TNFRSF9-5 as primary antibody against A549 (lane 2), HeLa (lane 3), Jurkat (lane 4), MCF7 (lane 5), H226 (lane 6), and PBMC (lane 7) whole cell lysates. Expected molecular weight - 27.9 kDa. Molecular weight standards are also included (lane 1).


Characterization SOP Files

  Western Blot - Tissue or Cell Lysate
Click to enlarge image Automated western blot using CPTC-TNFRSF9-5 as primary antibody against A549 (lane 2), HeLa (lane 3), Jurkat (lane 4), MCF7 (lane 5), H226 (lane 6), and PBMC (lane 7) whole cell lysates. Expected molecular weight - 27.9 kDa. Molecular weight standards are also included (lane 1). Click image to enlarge

CPTC-TNFRSF9-5 Automated Western Blot

Result: Negative

Automated western blot using CPTC-TNFRSF9-5 as primary antibody against A549 (lane 2), HeLa (lane 3), Jurkat (lane 4), MCF7 (lane 5), H226 (lane 6), and PBMC (lane 7) whole cell lysates. Expected molecular weight - 27.9 kDa. Molecular weight standards are also included (lane 1).


Characterization SOP Files

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Antibody: CPTC-TNFRSF9-6
Background

Catalog Number:

CPTC-TNFRSF9-6

Target Antigen:

TNF Receptor Superfamily Member 9 Peptide 1

Isotype:

IgG2b

Species:

Mouse Monoclonal Antibody

Last Updated:

10/04/2024

Antigen Recognition(s):

Peptide

Purchase
Characterization Data [Compare Characterization Data]
  NCI 60 Protein Array

CPTC-TNFRSF9-6 NCI 60 Protein Array

Result: Negative

This antibody is not suitable for use in a Reverse Phase Protein Array format as described in SOP M-105.


Characterization SOP Files

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Antigen: TNF Receptor Superfamily Member 9 Peptide 1
Background

NCI Identification Number:

00484

Antigen Name:

TNF Receptor Superfamily Member 9 Peptide 1

CPTC Name:

CPTC-TNFRSF9 Peptide 1

Aliases:

TNF Receptor Superfamily Member 9; CD137; Tumor Necrosis Factor Receptor Superfamily Member 9; T-Cell Antigen 4-1BB Homolog; 4-1BB Ligand Receptor; CD137 Antigen; CDw137; 4-1BB; ILA; Interleukin-Activated Receptor, Homolog Of Mouse Ly63; Tumor Necrosis Factor Receptor Superfamily, Member 9; Induced By Lymphocyte Activation (ILA); Homolog Of Mouse 4-1BB; Receptor Protein 4-1BB; T Cell Antigen ILA; T-Cell Antigen ILA; TNFRSF9

Function:

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.TNFRSF9 (TNF Receptor Superfamily Member 9) is a Protein Coding gene. Diseases associated with TNFRSF9 include Immunodeficiency 16 and Nodular Goiter. Among its related pathways are Innate Immune System and PEDF Induced Signaling. Gene Ontology (GO) annotations related to this gene include cytokine binding. An important paralog of this gene is TNFRSF21.Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.

Chromosomal Localization:

1p36.23

Accession Number:

NP_001552.2

UniProt Accession Number:

Q07011

DNA Source:

N/A

Immunogen:

Synthetic Peptide

Vector Name:

N/A

Extinction Coefficient:

Buffers:

Expressed Sequence:

NQICSPCPPNSFSSAGGQR

Native Sequence:

Calculated Isoelectric Point:

Molecular Weight:

2090

Last Updated:

03/24/2021

Links

Characterization Data

SOPs

No SOPs available.

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