TNF Receptor Superfamily Member 9 Peptide 1


Background

Catalog Number:

CPTC-TNFRSF9-5

Target Antigen:

TNF Receptor Superfamily Member 9 Peptide 1

Isotype:

IgG1

Species:

Mouse Monoclonal Antibody

Last Updated:

09/28/2021

Antigen Recognition(s):

Peptide

Thematic Panel(s):

Immuno-Oncology (IO)

Characterization Data [Compare Characterization Data]
Background

NCI Identification Number:

00484

Antigen Name:

TNF Receptor Superfamily Member 9 Peptide 1

CPTC Name:

CPTC-TNFRSF9 Peptide 1

Keywords:

TNF Receptor Superfamily Member 9; CD137; Tumor Necrosis Factor Receptor Superfamily Member 9; T-Cell Antigen 4-1BB Homolog; 4-1BB Ligand Receptor; CD137 Antigen; CDw137; 4-1BB; ILA; Interleukin-Activated Receptor, Homolog Of Mouse Ly63; Tumor Necrosis Factor Receptor Superfamily, Member 9; Induced By Lymphocyte Activation (ILA); Homolog Of Mouse 4-1BB; Receptor Protein 4-1BB; T Cell Antigen ILA; T-Cell Antigen ILA; TNFRSF9

Function:

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.TNFRSF9 (TNF Receptor Superfamily Member 9) is a Protein Coding gene. Diseases associated with TNFRSF9 include Immunodeficiency 16 and Nodular Goiter. Among its related pathways are Innate Immune System and PEDF Induced Signaling. Gene Ontology (GO) annotations related to this gene include cytokine binding. An important paralog of this gene is TNFRSF21.Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.

Chromosomal Localization:

1p36.23

NCBI Accession Number:

NP_001552.2

UniProt Accession Number:

Q07011

DNA Source:

N/A

Immunogen:

Synthetic Peptide

Vector Name:

N/A

Extinction Coefficient:

Buffers:

Expressed Sequence:

NQICSPCPPNSFSSAGGQR

Native Sequence:

Calculated Isoelectric Point:

Molecular Weight:

2090

Last Updated:

03/24/2021

Links

Characterization Data

SOPs

No SOPs available.

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