PRINT

RB Transcriptional Corepressor 1 Peptide 1

Antibody: CPTC-RB1-1
Background

Catalog Number:

CPTC-RB1-1

RRID:

AB_2722102

Target Antigen:

RB Transcriptional Corepressor 1 Peptide 1

Isotype:

IgG2c

Species:

Mouse Monoclonal Antibody

Last Updated:

09/01/2022

Antigen Recognition(s):

Peptide, Phosphorylation

Thematic Panel(s):

DNA Damage Response (DDR) Pathway

Purchase
Characterization Data [Compare Characterization Data]
  IHC HPA
Download This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org) (405.0 KB)

CPTC-RB1-1 Evaluation by the Human Protein Atlas

Result: Negative

This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org)


Characterization SOP Files

  Immunofluorescence - HPA
Download This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org) (405.0 KB)

CPTC-RB1-1 Evaluation by the Human Protein Atlas

Result: Negative

This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org)


Characterization SOP Files

  Indirect ELISA
Click to enlarge image Indirect ELISA (ie, binding of Antibody to biotinylated peptide coated on a NeutrAvidin plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding. Click image to enlarge

CPTC-RB1-1 peptide ELISA

Result: High Binding

Indirect ELISA (ie, binding of Antibody to biotinylated peptide coated on a NeutrAvidin plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.


Characterization SOP Files

  Indirect ELISA
Click to enlarge image Indirect ELISA (ie, binding of Antibody to biotinylated phospho-peptide coated on a NeutrAvidin plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding. Click image to enlarge

CPTC-RB1-1 phosho-peptide ELISA

Result: High Binding

Indirect ELISA (ie, binding of Antibody to biotinylated phospho-peptide coated on a NeutrAvidin plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.


Characterization SOP Files

[top]

Antibody: CPTC-RB1-2
Background

Catalog Number:

CPTC-RB1-2

RRID:

AB_2820275

Target Antigen:

RB Transcriptional Corepressor 1 Peptide 1

Isotype:

IgG

Species:

Rabbit Monoclonal Antibody

Last Updated:

09/01/2022

Antigen Recognition(s):

Peptide, Phosphorylation

Thematic Panel(s):

DNA Damage Response (DDR) Pathway

External Links
Purchase
Publications
Characterization Data [Compare Characterization Data]
  IHC HPA
Download This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org) (299.9 KB)

CPTC-RB1-2 Evaluation by the Human Protein Atlas

Result: Negative

This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org)


Characterization SOP Files

  Immuno-MRM
Click to enlarge image Immuno-MRM chromatogram of CPTC-RB1-2 antibody (see CPTAC assay portal for details: https://assays.cancer.gov/CPTAC-3288) Data provided by the Paulovich Lab, Fred Hutch (https://research.fredhutch.org/paulovich/en.html) Click image to enlarge

CPTC-RB1-2 iMRM

Result: Positive

Immuno-MRM chromatogram of CPTC-RB1-2 antibody (see CPTAC assay portal for details: https://assays.cancer.gov/CPTAC-3288)

Data provided by the Paulovich Lab, Fred Hutch (https://research.fredhutch.org/paulovich/en.html)


Characterization SOP Files

  Immunofluorescence - HPA
Download This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org) (299.9 KB)

CPTC-RB1-2 Evaluation by the Human Protein Atlas

Result: Negative

This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org)


Characterization SOP Files

[top]

Antibody: CPTC-RB1-3
Background

Catalog Number:

CPTC-RB1-3

RRID:

AB_2820276

Target Antigen:

RB Transcriptional Corepressor 1 Peptide 1

Isotype:

IgG

Species:

Rabbit Monoclonal Antibody

Last Updated:

09/01/2022

Antigen Recognition(s):

Peptide, Phosphorylation

Thematic Panel(s):

DNA Damage Response (DDR) Pathway

External Links
Purchase
Publications
Characterization Data [Compare Characterization Data]
  IHC HPA
Download This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org) (405.5 KB)

CPTC-RB1-3 Evaluation by the Human Protein Atlas

Result: Negative

This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org)


Characterization SOP Files

  Immuno-MRM
Click to enlarge image Immuno-MRM chromatogram of CPTC-RB1-3 antibody (see CPTAC assay portal for details: https://assays.cancer.gov/CPTAC-3251) Data provided by the Paulovich Lab, Fred Hutch (https://research.fredhutch.org/paulovich/en.html) Click image to enlarge

CPTC-RB1-3 iMRM

Result: Positive

Immuno-MRM chromatogram of CPTC-RB1-3 antibody (see CPTAC assay portal for details: https://assays.cancer.gov/CPTAC-3251)

Data provided by the Paulovich Lab, Fred Hutch (https://research.fredhutch.org/paulovich/en.html)


Characterization SOP Files

  Immunofluorescence - HPA
Download This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org) (405.5 KB)

CPTC-RB1-3 Evaluation by the Human Protein Atlas

Result: Negative

This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org)


Characterization SOP Files

[top]

Antigen: RB Transcriptional Corepressor 1 Peptide 1
Background

NCI Identification Number:

00099

Antigen Name:

RB Transcriptional Corepressor 1 Peptide 1

CPTC Name:

CPTC-RB1 Peptide 1

Aliases:

RB Transcriptional Corepressor 1; PPP1R130; RB; Protein Phosphatase 1, Regulatory Subunit 130; Prepro-Retinoblastoma-Associated Protein; Retinoblastoma 1; P110-RB1; P105-Rb; Pp110; PRb; Retinoblastoma Suspectibility Protein; Osteosarcoma; Rb; Mutant Retinoblastoma-Associated Protein; Retinoblastoma Susceptibility Protein; Mutated Retinoblastoma Protein; Retinoblastoma; RB1 Protein; Rb

Function:

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.RB1 (RB Transcriptional Corepressor 1) is a Protein Coding gene. Diseases associated with RB1 include Retinoblastoma and Familial Retinoblastoma. Among its related pathways are Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes and SARS-CoV-1 Genome Replication and Transcription. An important paralog of this gene is RBL2.

Chromosomal Localization:

13q14.2

Accession Number:

UniProt Accession Number:

P06400

DNA Source:

N/A

Immunogen:

Synthetic Peptide

Vector Name:

N/A

Extinction Coefficient:

Buffers:

Expressed Sequence:

IPGGNIYI(pS)PLK (pS807)

Native Sequence:

Calculated Isoelectric Point:

Molecular Weight:

1320

Last Updated:

07/01/2026

Links

Characterization Data

SOPs

No SOPs available.

[top]

Don't have Adobe Reader™?

Get it for free at Adobe.com

  [top]