Background
Catalog Number:
CPTC-NCAM1-1
Target Antigen:
Neural Cell Adhesion Molecule 1 Peptide 1
Isotype:
IgG
Species:
Rabbit Monoclonal Antibody
Last Updated:
02/09/2024
Antigen Recognition(s):
Peptide
Purchase
- DSHB CPTC-NCAM1-1
Characterization Data [Compare Characterization Data]
Western Blot - Recombinant Protein or Peptide
CPTC-NCAM1-1 Western Blot Recombinant Protein
Result: Negative
Western blot using CPTC-NCAM1-1 as primary antibody against human neural cell adhesion molecule 1 (NCAM1), transcript variant 2, recombinant protein (lane 2). Expected molecular weight - 94.4 kDa. Molecular weight standards are also included (lane 1).
Characterization SOP Files
Background
NCI Identification Number:
00384
Antigen Name:
Neural Cell Adhesion Molecule 1 Peptide 1
CPTC Name:
CPTC-NCAM1 Peptide 1
Aliases:
Neural Cell Adhesion Molecule 1; NCAM; CD56; Antigen Recognized By Monoclonal Antibody 5.1H11; Neural Cell Adhesion Molecule, NCAM; CD56 Antigen; N-CAM-1; NCAM-1; MSK39; NCAM1
Function:
This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. NCAM1 (Neural Cell Adhesion Molecule 1) is a Protein Coding gene. Diseases associated with NCAM1 include Rabies and Bile Duct Cancer. Among its related pathways are Neuroscience and RET signaling. Gene Ontology (GO) annotations related to this gene include identical protein binding. An important paralog of this gene is NCAM2.This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. (Microbial infection) Acts as a receptor for rabies virus. Cell adhesion molecules (CAMs) are a large family of transmembrane proteins that are involved in the binding of a cell to another cell or to the extracellular matrix. They have roles in cell proliferation, differentiation, motility, trafficking, apoptosis and tissue architecture.
Chromosomal Localization:
11q23.2
Accession Number:
NP_000606.3
UniProt Accession Number:
P13591
DNA Source:
N/A
Immunogen:
Synthetic Peptide
Vector Name:
N/A
Extinction Coefficient:
Buffers:
Expressed Sequence:
GLGEISAASEFK
Native Sequence:
Calculated Isoelectric Point:
Molecular Weight:
1320
Last Updated:
09/02/2020
Links
- CPTAC Assay Portal - EnsEMBL NCAM1
- CPTAC Assay Portal - Entrez NCAM1
- Uniprot - Uniprot P13591
Characterization Data
SOPs
No SOPs available.
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