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Myosin Light Chain 3 Peptide 1

Antibody: CPTC-MYL3-1
Background

Catalog Number:

CPTC-MYL3-1

Target Antigen:

Myosin Light Chain 3 Peptide 1

Isotype:

IgG

Species:

Rabbit Recombinant Cloned Antibody

Last Updated:

10/19/2023

Antigen Recognition(s):

Peptide

Characterization Data [Compare Characterization Data]
  IHC HPA
Download Results provided by the Human Protein Atlas (www.proteinatlas.org). (423.4 KB)

CPTC-MYL3-1 evaluation by the Human Protein Atlas

Result: Negative

Results provided by the Human Protein Atlas (www.proteinatlas.org).


Characterization SOP Files

  Immuno-MRM
Click to enlarge image iMRM data obtained using antibody CPTC-MYL3-1 to immuno-precipitate peptide ALGQNPTQAEVLR (CPTC-MYL3 Peptide 1) Data provided by the Carr Lab, Broad Institute https://www.broadinstitute.org/proteomics/protocols Click image to enlarge

CPTC-MYL3-1 iMRM

Result: Positive

iMRM data obtained using antibody CPTC-MYL3-1 to immuno-precipitate peptide ALGQNPTQAEVLR (CPTC-MYL3 Peptide 1)

Data provided by the Carr Lab, Broad Institute
https://www.broadinstitute.org/proteomics/protocols


Characterization SOP Files

  Immunofluorescence - HPA
Download Results provided by the Human Protein Atlas (www.proteinatlas.org). (423.4 KB)

CPTC-MYL3-1 evaluation by the Human Protein Atlas

Result: Negative

Results provided by the Human Protein Atlas (www.proteinatlas.org).


Characterization SOP Files

  Western Blot - Recombinant Protein or Peptide

CPTC-MYL3-1 Recombinant Protein WB

Result: Negative

Automated Western Blot with recombinant MYL3 protein


Characterization SOP Files

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Antigen: Myosin Light Chain 3 Peptide 1
Background

NCI Identification Number:

00331

Antigen Name:

Myosin Light Chain 3 Peptide 1

CPTC Name:

CPTC-MYL3 Peptide 1

Aliases:

Myosin Light Chain 3; MLC1SB; Myosin, Light Polypeptide 3, Alkali; Ventricular, Skeletal, Slow; Myosin Light Chain 1, Slow-Twitch Muscle B/Ventricular Isoform; Myosin, Light Chain 3, Alkali; Ventricular, Skeletal, Slow; Ventricular/Slow Twitch Myosin Alkali Light Chain; Ventricular Myosin Alkali Light Chain; Ventricular Myosin Light Chain 1; Cardiac Myosin Light Chain 1; MLC-LV/Sb; MLC1V; CMLC1; CMH8; VLC1; VLCl; MYL3

Function:

MYL3 encodes myosin light chain 3, an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy. MYL3 (Myosin Light Chain 3) is a Protein Coding gene. Diseases associated with MYL3 include Cardiomyopathy, Familial Hypertrophic, 8 and Hypertrophic Cardiomyopathy. Among its related pathways are Guidance Cues and Growth Cone Motility and Activation of cAMP-Dependent PKA. Gene Ontology (GO) annotations related to this gene include calcium ion binding and structural constituent of muscle. An important paralog of this gene is MYL4.Regulatory light chain of myosin. Does not bind calcium. Myosins are a large family of motor proteins that share the common features of ATP hydrolysis (ATPase enzyme activity), actin binding and potential for kinetic energy transduction. Originally isolated from muscle cells, almost all eukaryotic cells are known to contain myosins.

Chromosomal Localization:

3p21.31

Accession Number:

NP_000249.1

UniProt Accession Number:

P08590

DNA Source:

N/A

Immunogen:

Synthetic Peptide

Vector Name:

N/A

Extinction Coefficient:

Buffers:

Expressed Sequence:

ALGQNPTQAEVLR

Native Sequence:

Calculated Isoelectric Point:

Molecular Weight:

1430

Last Updated:

08/23/2020

Links

Characterization Data

SOPs

No SOPs available.

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