Forkhead Box C2 Peptide 1
Rabbit Monoclonal Antibody
Peptide, Recombinant Full-length
Epithelial Mesenchymal Transition (EMT)
Immuno-precipitation data obtained incubating CPTC-FOXC2-1 and the recombinant domain of FOXC2 (aa10-70, expected, MW ~10KDa)
Indirect ELISA using CPTC-FOXC2-1 as primary antibody against FOXC2 domain comprising amino acids 1-70.
Western Blot using CPTC-FOXC2-1 as primary Ab against recombinant FOXC2 protein (lane 2). Also included are molecular wt. standards (lane 1).
Western blot using CPTC-FOXC2-1 as primary antibody against FOXC2 protein domain comprising amino acids 1-70 (lane 2). Molecular weight standards are also included (lane 1).
Western Blot using CPTC-FOXC2-1 as primary antibody against cell lysates A549, H226, HeLa, Jurkat and MCF7. Expected MW of 53.7 KDa. All cell lysates negative. Molecular weight standards are also included (lane 1).
Automated Western Blot using CPTC-FOXC2-1 as primary antibody against cell lysates A549, H226, HeLa, Jurkat and MCF7. Expected MW of 53.7 KDa. All cell lysates negative. Molecular weight standards are also included (lane 1).
NCI Identification Number:
Forkhead Box C2 Peptide 1
CPTC-FOXC2 Peptide 1
Forkhead Box C2; Forkhead Box C2 (MFH-1, Mesenchyme Forkhead 1; Forkhead-Related Protein FKHL14; Mesenchyme Fork Head Protein 1; Transcription Factor FKH-14; Mesenchyme Forkhead 1; FKHL14; MFH1; Forkhead, Drosophila, Homolog-Like 14; MFH-1,Mesenchyme Forkhead 1; Forkhead Box Protein C2; MFH-1 Protein; MFH-1 ; LD
This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of mesenchymal tissues.
FOXC2 (Forkhead Box C2) is a Protein Coding gene. Diseases associated with FOXC2 include Lymphedema-Distichiasis Syndrome and Distichiasis. Among its related pathways are Adipogenesis and Glucose / Energy Metabolism. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and transcription regulatory region DNA binding. An important paralog of this gene is FOXC1.
Transcriptional activator. Might be involved in the formation of special mesenchymal tissues.
UniProt Accession Number:
The NCI acknowledges the generous advice and gene clones provided by Robert A. Weinberg at the Ludwig Center for Cancer Research of the Massachusetts Institute of Technology. These reagents have been provided by the Division of Cancer Treatment and Diagnosis (DCTD) of the National Cancer Institute (NCI) using funding of the American Recovery and Reinvestment Act of 2009
Calculated Isoelectric Point:
No SOPs available.
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