Cell Division Cycle Associated 8 Peptide 1


Background

Catalog Number:

CPTC-CDCA8-1

Target Antigen:

Cell Division Cycle Associated 8 Peptide 1

Isotype:

IgG

Species:

Rabbit Recombinant Cloned Antibody

Last Updated:

02/19/2020

Antigen Recognition(s):

Peptide, Phosphorylation

Background

NCI Identification Number:

00295

Antigen Name:

Cell Division Cycle Associated 8 Peptide 1

CPTC Name:

CPTC-CDCA8 Peptide 1

Keywords:

Cell Division Cycle Associated 8; Borealin; Pluripotent Embryonic Stem Cell-Related Gene 3 Protein; Cell Division Cycle-Associated Protein 8; HDasra-B; Dasra-B; BOREALIN; Dasra B; PESCRG3; DasraB; MESRGP; BOR

Function:

This gene encodes a component of the chromosomal passenger complex. This complex is an essential regulator of mitosis and cell division. This protein is cell-cycle regulated and is required for chromatin-induced microtubule stabilization and spindle formation. Alternate splicing results in multiple transcript variants. Pseudgenes of this gene are found on chromosomes 7, 8 and 16.CDCA8 (Cell Division Cycle Associated 8) is a Protein Coding gene. Among its related pathways are Signaling by Rho GTPases and Mitotic Metaphase and Anaphase.Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment.

Chromosomal Localization:

1p34.3

NCBI Accession Number:

na

UniProt Accession Number:

Q53HL2

DNA Source:

N/A

Immunogen:

Synthetic Peptide

Vector Name:

N/A

Extinction Coefficient:

Buffers:

Expressed Sequence:

CLTAEAIQT(ph)PLK

Native Sequence:

Calculated Isoelectric Point:

Molecular Weight:

1320

Last Updated:

10/22/2019

Links

Characterization Data

SOPs

No SOPs available.

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