Background
Catalog Number:
CPTC-OXTR-1
RRID:
AB_2943354
Target Antigen:
Oxytocin Receptor Peptide 1
Isotype:
IgG
Species:
Rabbit Monoclonal Antibody
Last Updated:
05/15/2025
Antigen Recognition(s):
Peptide
Characterization Data [Compare Characterization Data]
Background
Catalog Number:
CPTC-OXTR-2
Target Antigen:
Oxytocin Receptor Peptide 1
Isotype:
IgG
Species:
Rabbit Monoclonal Antibody
Last Updated:
03/18/2025
Antigen Recognition(s):
Peptide
Characterization Data [Compare Characterization Data]
Background
NCI Identification Number:
00551
Antigen Name:
Oxytocin Receptor Peptide 1
CPTC Name:
CPTC-OXTR Peptide 1
Aliases:
Oxytocin Receptor; OTR; OT-R
Function:
The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition.OXTR (Oxytocin Receptor) is a Protein Coding gene. Diseases associated with OXTR include Rippling Muscle Disease 2 and Long Qt Syndrome 9. Among its related pathways are Class A/1 (Rhodopsin-like receptors) and GPCR downstream signalling. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and peptide hormone binding. An important paralog of this gene is AVPR1B.Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.Oxytocin receptors (OT) are G-protein-coupled receptors that mediate parturition and lactation. They are closely related to vasopressin receptors. Oxytocin receptors are coupled to Gq/11 proteins and are localized to the myoepithelial cells of the mammary gland.
Chromosomal Localization:
3p25.3
Accession Number:
UniProt Accession Number:
P30559
DNA Source:
N/A
Immunogen:
Synthetic Peptide
Vector Name:
N/A
Extinction Coefficient:
Buffers:
Expressed Sequence:
CSASYLKGRRLGETSA
Native Sequence:
Calculated Isoelectric Point:
Molecular Weight:
1759
Last Updated:
07/27/2023
Links
- EnsEMBL - EnsEMBL OXTR
- Uniprot - Uniprot P30559
Characterization Data
SOPs
No SOPs available.
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