Background
Catalog Number:
CPTC-XMRV P12-1
RRID:
AB_10805282
Target Antigen:
Xenotropic murine leukemia virus-related virus P12
Isotype:
IgG1
Species:
Mouse Monoclonal Antibody
Last Updated:
11/26/2019
Antigen Recognition(s):
Recombinant Full-length
Purchase
- DSHB CPTC-XMRV P12-1
Characterization Data [Compare Characterization Data]
Indirect ELISA
CPTC-XMRVP12-1 Indirect ELISA
Result: Positive
Indirect ELISA (ie, binding of Antibody to Antigen coated plate)
Characterization SOP Files
NCI 60 Protein Array
CPTC-XMRVP12-1 NCI 60 Protein Array
Result: Negative
This antibody is not suitable for use in a Reverse Phase Protein Array format as described in SOP M-105.
Characterization SOP Files
Western Blot - Recombinant Protein or Peptide
CPTC-XMRVP12-1 Western blot
Result: Positive
Western Blot using CPTC-XMRVP12-1 as primary Ab against XMRVP12 - Ag00003 (lane 2). Also included are molecular wt. standards (lane 1) and mouse IgG control (lane 3).
Characterization SOP Files
Background
Catalog Number:
CPTC-XMRV P12-2
RRID:
AB_10805154
Target Antigen:
Xenotropic murine leukemia virus-related virus P12
Isotype:
IgG2b
Species:
Mouse Monoclonal Antibody
Last Updated:
11/26/2019
Antigen Recognition(s):
Recombinant Full-length
Purchase
- DSHB CPTC-XMRV P12-2
Characterization Data [Compare Characterization Data]
Indirect ELISA
CPTC-XMRVP12-2 Indirect ELISA
Result: Positive
Indirect ELISA (ie, binding of Antibody to Antigen coated plate)
Characterization SOP Files
NCI 60 Protein Array
CPTC-XMRVP12-2 NCI 60 Protein Array
Result: Negative
This antibody is not suitable for use in a Reverse Phase Protein Array format as described in SOP M-105.
Characterization SOP Files
Western Blot - Recombinant Protein or Peptide
CPTC-XMRVP12-2 Western blot
Result: Positive
Western Blot using CPTC-XMRVP12-2 as primary Ab against XMRVP12 Ag00003 (lane 2). Also included are molecular wt. standards (lane 1) and mouse IgG control (lane 3).
Characterization SOP Files
Background
Catalog Number:
CPTC-XMRV P12-3
RRID:
AB_10805427
Target Antigen:
Xenotropic murine leukemia virus-related virus P12
Isotype:
IgG1
Species:
Mouse Monoclonal Antibody
Last Updated:
11/26/2019
Antigen Recognition(s):
Recombinant Full-length
Purchase
- DSHB CPTC-XMRV P12-3
Characterization Data [Compare Characterization Data]
Indirect ELISA
CPTC-XMRVP12-3 Indirect ELISA
Result: Positive
Indirect ELISA (ie, binding of Antibody to Antigen coated plate)
Characterization SOP Files
NCI 60 Protein Array
CPTC-XMRVP12-3 NCI 60 Protein Array
Result: Negative
This antibody is not suitable for use in a Reverse Phase Protein Array format as described in SOP M-105.
Characterization SOP Files
Western Blot - Recombinant Protein or Peptide
CPTC-XMRVP12-3 Western blot
Result: Positive
Western Blot using CPTC-XMRVP12-3 as primary Ab against XMRVP12 Ag00003 (lane 2). Also included are molecular wt. standards (lane 1) and mouse IgG control (lane 3).
Characterization SOP Files
Background
NCI Identification Number:
00003
Antigen Name:
Xenotropic murine leukemia virus-related virus P12
CPTC Name:
CPTC-XMRV P12
Aliases:
Function:
XMRV belongs to the virus family Retroviridae and the genus gammaretrovirus that was first described in 2006. It has a single-stranded RNA genome that replicates through a DNA intermediate. Its name refers to its close relationship with the murine leukemia viruses (â??MuLVsâ?). The genome, approximately 8100 nucleotides in length, is 95% identical with several endogenous retroviruses of mice, and is 93-94% identical with several exogenous mouse viruses. XMRV has been isolated from human biological samples. Several reports have associated the virus with prostate cancer,and chronic fatigue syndrome (CFS). It has not yet been established whether XMRV is a cause of disease.
Chromosomal Localization:
Expression System:
E. coli
Accession Number:
xxx
UniProt Accession Number:
DNA Source:
N/A
Immunogen:
Recombinant Full Length Protein
Vector Name:
pDest-522
Extinction Coefficient:
Buffers:
Expressed Sequence:
MHHHHHHPALTPSIKSKPPKPQVLPDSGGPLIDLLTEDPPPYGAQPSSSA
RENNEEEAATTSEVSPPSPMVSRLRGRRDPPAADSTTSQAF
Native Sequence:
Calculated Isoelectric Point:
6.02
Molecular Weight:
9700
Last Updated:
07/24/2020
Links
Characterization Data
Gel
Click image to enlarge
CPTC-XMRVP12
PAGE of XMRVP12 (Ag 0003) with molecular weight standards in lane 1
Characterization SOP Files
SOPs
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