Background
Catalog Number:
CPTC-VSIR-1
RRID:
AB_2890094
Target Antigen:
V-Set Immunoregulatory Receptor Peptide 1
Isotype:
IgG
Species:
Rabbit Monoclonal Antibody
Last Updated:
05/17/2024
Antigen Recognition(s):
Peptide
Purchase
- DSHB CPTC-VSIR-1
Characterization Data [Compare Characterization Data]
NCI 60 Protein Array
CPTC-VSIR-1 NCI 60 Protein Array
Result: Negative
This antibody is not suitable for use in a Reverse Phase Protein Array format as described in SOP M-105.
Characterization SOP Files
Western Blot - Tissue or Cell Lysate
CPTC-VSIR-1 Simple Western (Cell lysates)
Result: Negative
Automated WB (Simple Western) using CPTC-VSIR-1 as primary antibody against the whole lysate of PBMC, HeLa, Jurkat, A549, MCF7 and H226. Expected MW is 34 Kda. The antibody does not recognize the target in tested lysates.
Characterization SOP Files
Background
NCI Identification Number:
00349
Antigen Name:
V-Set Immunoregulatory Receptor Peptide 1
CPTC Name:
CPTC-VSIR Peptide 1
Aliases:
V-Set Immunoregulatory Receptor; SISP1; VISTA; V-Type Immunoglobulin Domain-Containing Suppressor Of T-Cell Activation; V-Set Domain-Containing Immunoregulatory Receptor; V-Domain Ig Suppressor Of T Cell Activation; Stress-Induced Secreted Protein-1; PDCD1 Homolog; C10orf54; Sisp-1; B7-H5; Dies1; PD-1H; B7H5; GI24; Chromosome 10 Open Reading Frame 54; Stress Induced Secreted Protein 1; Platelet Receptor GI24; Platelet Receptor Gi24; Death Domain1alpha; DD1alpha; PP2135; VSIR
Function:
VSIR (V-Set Immunoregulatory Receptor) is a Protein Coding gene. Diseases associated with VSIR include Ichthyosis, Congenital, Autosomal Recessive 6 and Monckeberg Arteriosclerosis. Among its related pathways are Cell adhesion molecules (CAMs) and NF-kappaB Signaling. An important paralog of this gene is VSIG8.Immunoregulatory receptor which inhibits the T-cell response (PubMed:24691993). May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (By similarity). May stimulate MMP14-mediated MMP2 activation
Chromosomal Localization:
10q22.1
Accession Number:
NP_071436.1
UniProt Accession Number:
Q9H7M9
DNA Source:
N/A
Immunogen:
Synthetic Peptide
Vector Name:
N/A
Extinction Coefficient:
Buffers:
Expressed Sequence:
VHGAMELQVQTGK
Native Sequence:
Calculated Isoelectric Point:
Molecular Weight:
1430
Last Updated:
09/02/2020
Links
- EnsEMBL - EnsEMBL VSIR
- Entrez - Entrez VSIR
- Uniprot - Uniprot Q9H7M9
Characterization Data
SOPs
No SOPs available.
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