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Tubulin Beta Class I Peptide 1

Antibody: CPTC-TUBB-1
Background

Catalog Number:

CPTC-TUBB-1

RRID:

AB_2877665

Target Antigen:

Tubulin Beta Class I Peptide 1

Isotype:

IgG

Species:

Rabbit Recombinant Cloned Antibody

Last Updated:

02/09/2024

Antigen Recognition(s):

Peptide

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Characterization Data [Compare Characterization Data]
  IHC HPA
Download This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org) (323.7 KB)

CPTC-TUBB-1 Evaluation by the Human Protein Atlas

Result: Negative

This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org)


Characterization SOP Files

  IHC Tissue

CTPC-TUBB-1 IHC Tissue

Result: Negative

This antibody is not suitable for use in an Immunohistochemistry format as described in SOP M-106.


Characterization SOP Files

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Antigen: Tubulin Beta Class I Peptide 1
Background

NCI Identification Number:

00306

Antigen Name:

Tubulin Beta Class I Peptide 1

CPTC Name:

CPTC-TUBB Peptide 1

Aliases:

Tubulin Beta Class I; Tubulin, Beta Polypeptide; Tubulin Beta-5 Chain; Tubulin Beta Chain; TUBB5; Epididymis Secretory Sperm Binding Protein; Tubulin, Beta Class I; Tubulin Beta-1 Chain; Class I Beta-Tubulin; Beta Ib Tubulin; Beta1-Tubulin; Tubulin, Beta; OK/SW-Cl.56; CDCBM6; CSCSC1; TUBB1; M40

Function:

This gene encodes a beta tubulin protein. This protein forms a dimer with alpha tubulin and acts as a structural component of microtubules. Mutations in this gene cause cortical dysplasia, complex, with other brain malformations 6. Alternative splicing results in multiple splice variants. There are multiple pseudogenes for this gene on chromosomes 1, 6, 7, 8, 9, and 13.TUBB (Tubulin Beta Class I) is a Protein Coding gene. Diseases associated with TUBB include Cortical Dysplasia, Complex, With Other Brain Malformations 6 and Skin Creases, Congenital Symmetric Circumferential, 1. Among its related pathways are Innate Immune System and Development Slit-Robo signaling. Gene Ontology (GO) annotations related to this gene include GTP binding and structural molecule activity. An important paralog of this gene is TUBB4B.Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Microtubules are cylindrical tubes of 20-25 nm in diameter. They are composed of protofilaments which are in turn composed of alpha- and beta-tubulin polymers. Each microtubule is polarized; at one end alpha-subunits are exposed (-) and at the other, beta-subunits are exposed (+).

Chromosomal Localization:

6p21.33

Accession Number:

NP_001280141.1

UniProt Accession Number:

P07437

DNA Source:

N/A

Immunogen:

Synthetic Peptide

Vector Name:

N/A

Extinction Coefficient:

Buffers:

Expressed Sequence:

CISVYYNEATGGK

Native Sequence:

Calculated Isoelectric Point:

Molecular Weight:

1430

Last Updated:

08/21/2020

Links

Characterization Data

SOPs

No SOPs available.

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