PRINT

TNF Receptor Superfamily Member 17 Peptide 1

Antibody: CPTC-TNFRSF17-1
Background

Catalog Number:

CPTC-TNFRSF17-1

Target Antigen:

TNF Receptor Superfamily Member 17 Peptide 1

Isotype:

IgG

Species:

Rabbit Recombinant Cloned Antibody

Last Updated:

02/16/2024

Antigen Recognition(s):

Peptide, Phosphorylation

Thematic Panel(s):

Immuno-Oncology (IO)

External Links
Purchase
Publications
Characterization Data [Compare Characterization Data]
  IHC HPA
Download This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org) (464.7 KB)

CPTC-TNFRSF17-1 Evaluation by the Human Protein Atlas

Result: Negative

This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org)


Characterization SOP Files

  IHC Tissue

CTPC-TNFRSF17-1 IHC Tissue

Result: Negative

This antibody is not suitable for use in an Immunohistochemistry format as described in SOP M-106.


Characterization SOP Files

  Western Blot - Tissue or Cell Lysate
Click to enlarge image Western blot using CPTC-TNFRSF17-1 as primary antibody against LCL57 cell lysate. Cell lysate was irradiated with 10 Gy as shown in the ‘+’ indicated lane. Non-irradiated cell lysate was treated with alkaline phosphatase enzyme as shown in ‘-‘ indicated lane. Blots were developed using enhanced chemiluminescence. Molecular weight standards are also included. Click image to enlarge

CPTC-TNFRSF17-1 western blot (cell lysate)

Result: Negative

Western blot using CPTC-TNFRSF17-1 as primary antibody against LCL57 cell lysate. Cell lysate was irradiated with 10 Gy as shown in the ‘+’ indicated lane. Non-irradiated cell lysate was treated with alkaline phosphatase enzyme as shown in ‘-‘ indicated lane. Blots were developed using enhanced chemiluminescence. Molecular weight standards are also included.


Characterization SOP Files

[top]

Antigen: TNF Receptor Superfamily Member 17 Peptide 1
Background

NCI Identification Number:

00298

Antigen Name:

TNF Receptor Superfamily Member 17 Peptide 1

CPTC Name:

CPTC-TNFRSF17 Peptide 1

Aliases:

TNF Receptor Superfamily Member 17; Tumor Necrosis Factor Receptor Superfamily Member 17; B-Cell Maturation Protein; BCMA; BCM; Tumor Necrosis Factor Receptor Superfamily, Member 17; B Cell Maturation Antigen; B-Cell Maturation Factor; CD269 Antigen; TNFRSF13A; CD269

Function:

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. TNFRSF17 (TNF Receptor Superfamily Member 17) is a Protein Coding gene. Diseases associated with TNFRSF17 include Autoimmune Disease and Common Variable Immunodeficiency. Among its related pathways are PEDF Induced Signaling and Innate Immune System. An important paralog of this gene is TNFRSF13C.Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.

Chromosomal Localization:

16p13.13

Accession Number:

NP_001183.2

UniProt Accession Number:

Q02223

DNA Source:

N/A

Immunogen:

Synthetic Peptide

Vector Name:

N/A

Extinction Coefficient:

Buffers:

Expressed Sequence:

CSLPAALS(ph)ATEIEK

Native Sequence:

Calculated Isoelectric Point:

Molecular Weight:

1540

Last Updated:

08/21/2020

Links

Characterization Data

SOPs

No SOPs available.

[top]

Don't have Adobe Reader™?

Get it for free at Adobe.com

  [top]