Ribonucleotide Reductase M2 Peptide 2


Background

Catalog Number:

CPTC-RRM2-2

Target Antigen:

Ribonucleotide Reductase M2 Peptide 2

Isotype:

IgG

Species:

Rabbit Monoclonal Antibody

Last Updated:

03/31/2015

Antigen Recognition(s):

Purchase
Characterization Data [Compare Characterization Data]
  Indirect ELISA
Click to enlarge image Indirect ELISA (ie, binding of Antibody to biotinylated peptide coated on a NeutrAvidin plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding. Click image to enlarge

CPTC-RRM2-2 Indirect ELISA (peptide)

Indirect ELISA (ie, binding of Antibody to biotinylated peptide coated on a NeutrAvidin plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.

Characterization SOP Files

  Indirect ELISA
Click to enlarge image Indirect ELISA (ie, binding of Antibody to full-length Antigen coated on plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding. Click image to enlarge

CPTC-RRM2-2 Indirect ELISA

Indirect ELISA (ie, binding of Antibody to full-length Antigen coated on plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.

Background

NCI Identification Number:

00039

Antigen Name:

Ribonucleotide Reductase M2 Peptide 2

CPTC Name:

CPTC-RRM2 Peptide 2

Keywords:

Ribonucleotide Reductase M2 Polypeptide; Ribonucleotide Reductase Small Chain; Ribonucleotide Reductase Small Subunit; RR2; EC 1.17.4.1; R2; RR2M; Ribonucleoside-Diphosphate Reductase Subunit M2

Function:

This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the
formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a
cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1
and X.

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.

Chromosomal Localization:

2p25-p24

Expression System:

NCBI Accession Number:

NP_001025.1

Swiss Prot Accession Number:

P31350

DNA Source:

N/A

Immunogen:

Synthetic Peptide

Vector Name:

N/A

Extinction Coefficient:

Buffers:

Expressed Sequence:

DIQHWESLKPEER

Native Sequence:

Calculated Isoelectric Point:

0

Molecular Weight:

1430

Last Updated:

06/21/2013

Links

Characterization Data

SOPs

No SOPs available.

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