Background
Catalog Number:
CPTC-Ly6K-4
Target Antigen:
Lymphocyte Antigen 6 Family Member K Peptide 1
Isotype:
IgG
Species:
Rabbit Monoclonal Antibody
Last Updated:
02/09/2024
Antigen Recognition(s):
Peptide
Purchase
- DSHB CPTC-Ly6K-4
Characterization Data [Compare Characterization Data]
Affinity Measurement by SPR
CPTC-LY6K-4 Affinity and Kinetics (Surface Plasmon Resonance)
Result: Negative
Affinity and binding kinetics of CPTC-LY6K-4 and full length LY6K recombinant protein were measured using surface plasmon resonance. LY6K recombinant protein was amine coupled onto a Series S CM5 chip. CPTC-LY6K-4 antibody was used as analyte and was titrated at 1024 nM, 256 nM, 64 nM, 16 nM, 4 nM, 1 nM, 0.25 nM, and 0.0625 nM. All binding data were double-referenced and analyzed globally using a bivalent fitting model.
Characterization SOP Files
Background
NCI Identification Number:
00543
Antigen Name:
Lymphocyte Antigen 6 Family Member K Peptide 1
CPTC Name:
CPTC-Ly6K Peptide 1
Aliases:
Lymphocyte Antigen 6 Family Member K; Lymphocyte Antigen 6 Complex, Locus K; Cancer/Testis Antigen 97; Ly-6K; Up-Regulated In Lung Cancer 10; Lymphocyte Antigen 6K; HSJ001348; URLC10; CT97; CO16; FLJ35226
Function:
Predicted to be involved in binding activity of sperm to zona pellucida. Predicted to act upstream of or within flagellated sperm motility. Predicted to be located in cell surface; cytoplasm; and plasma membrane. Predicted to be active in acrosomal vesicle. [provided by Alliance of Genome Resources, Apr 2022]LY6K (Lymphocyte Antigen 6 Family Member K) is a Protein Coding gene. Diseases associated with LY6K include Lung Cancer. Among its related pathways are Metabolism of proteins and Post-translational modification: synthesis of GPI-anchored proteins. An important paralog of this gene is GML.Required for sperm migration into the oviduct and male fertility by controlling binding of sperm to zona pellucida (By similarity). May play a role in cell growth.
Chromosomal Localization:
8q24.3
Accession Number:
NP_001153826.1
UniProt Accession Number:
Q17RY6
DNA Source:
N/A
Immunogen:
Synthetic Peptide
Vector Name:
N/A
Extinction Coefficient:
Buffers:
Expressed Sequence:
ERPKPEEKRFLLEEPC and AKQCSAGCAAMERPK
Native Sequence:
Calculated Isoelectric Point:
Molecular Weight:
1760
Last Updated:
03/06/2023
Links
- EnsEMBL - EnsEMBL Ly6K
- Entrez - EnsEMBL Ly6K
- Uniprot - Uniprot Q17RY6
Characterization Data
SOPs
No SOPs available.
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