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Jun Proto-Oncogene Peptide 2

Antibody: CPTC-JUN-5
Background

Catalog Number:

CPTC-JUN-5

RRID:

AB_2888955

Target Antigen:

Jun Proto-Oncogene Peptide 2

Isotype:

IgG

Species:

Rabbit Monoclonal Antibody

Last Updated:

01/04/2023

Antigen Recognition(s):

Peptide, Phosphorylation

Thematic Panel(s):

DNA Damage Response (DDR) Pathway

Purchase
External Links
Characterization Data [Compare Characterization Data]
  IHC HPA
Download This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org) (151.2 KB)

CPTC-JUN-5 Evaluation by the Human Protein Atlas

Result: Positive

This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org)


Characterization SOP Files

  Immunofluorescence - HPA
Click to enlarge image Results provided by the Human Protein Atlas (www.proteinatlas.org). The subcellular location is supported by literature. Immunofluorescent staining of human cell line U2OS shows localization to nucleoplasm. Human assay: THP-1 fixed with PFA, dilution: 1:100 Human assay: U2OS fixed with PFA, dilution: 1:100 Click image to enlarge

CPTC-JUN-5 Evaluation by the Human Protein Atlas

Result: Positive

Results provided by the Human Protein Atlas (www.proteinatlas.org). The subcellular location is supported by literature. Immunofluorescent staining of human cell line U2OS shows localization to nucleoplasm.
Human assay: THP-1 fixed with PFA, dilution: 1:100
Human assay: U2OS fixed with PFA, dilution: 1:100


Characterization SOP Files

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Antibody: CPTC-JUN-6
Background

Catalog Number:

CPTC-JUN-6

RRID:

AB_2888956

Target Antigen:

Jun Proto-Oncogene Peptide 2

Isotype:

IgG

Species:

Rabbit Monoclonal Antibody

Last Updated:

01/04/2023

Antigen Recognition(s):

Peptide, Phosphorylation

Thematic Panel(s):

DNA Damage Response (DDR) Pathway

Purchase
External Links
Characterization Data [Compare Characterization Data]
  IHC HPA
Download This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org) (279.5 KB)

CPTC-JUN-6 Evaluation by the Human Protein Atlas

Result: Negative

This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org)


Characterization SOP Files

  Immunofluorescence - HPA
Click to enlarge image Results provided by the Human Protein Atlas (www.proteinatlas.org). The subcellular location is supported by literature. Immunofluorescent staining of human cell line U2OS shows localization to nucleoplasm. Human assay: THP-1 fixed with PFA, dilution: 1:100 Human assay: U2OS fixed with PFA, dilution: 1:100 Click image to enlarge

CPTC-JUN-6 Evaluation by the Human Protein Atlas

Result: Positive

Results provided by the Human Protein Atlas (www.proteinatlas.org). The subcellular location is supported by literature. Immunofluorescent staining of human cell line U2OS shows localization to nucleoplasm. Human assay: THP-1 fixed with PFA, dilution: 1:100
Human assay: U2OS fixed with PFA, dilution: 1:100


Characterization SOP Files

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Antigen: Jun Proto-Oncogene Peptide 2
Background

NCI Identification Number:

00240

Antigen Name:

Jun Proto-Oncogene Peptide 2

CPTC Name:

CPTC-JUN Peptide 2

Aliases:

V-Jun Avian Sarcoma Virus 17 Oncogene Homolog; JUN oncogene; Activator Protein 1; Proto-Oncogene C-Jun; AP1; p39; V-Jun Sarcoma Virus 17 Oncogene Homolog; AP-1; c-JUN; Enhancer-Binding Protein AP1; Jun Activation Domain Binding Protein; Transcription Factot AP-1

Function:

This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.

JUN (jun proto-oncogene) is a protein-coding gene. Diseases associated with JUN include sarcoma, and campylobacteriosis. GO annotations related to this gene include transcription coactivator activity and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is JUND.

Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.

Chromosomal Localization:

1p32-p31

Accession Number:

NP_002219.1

UniProt Accession Number:

P05412

DNA Source:

N/A

Immunogen:

Synthetic Peptide

Vector Name:

N/A

Extinction Coefficient:

Buffers:

Expressed Sequence:

EEPQTVPEMPGETPPLS(ph)PIDMESQER (pS243)

Native Sequence:

Calculated Isoelectric Point:

0

Molecular Weight:

2860

Last Updated:

02/26/2018

Links

Characterization Data

SOPs

No SOPs available.

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