Jun Proto-Oncogene Peptide 2


Background

Catalog Number:

CPTC-JUN-5

Target Antigen:

Jun Proto-Oncogene Peptide 2

Isotype:

IgG

Species:

Rabbit Monoclonal Antibody

Last Updated:

03/08/2018

Antigen Recognition(s):

peptide, phosphorylation

Background

Catalog Number:

CPTC-JUN-6

Target Antigen:

Jun Proto-Oncogene Peptide 2

Isotype:

IgG

Species:

Rabbit Monoclonal Antibody

Last Updated:

03/08/2018

Antigen Recognition(s):

peptide, phosphorylation

Background

NCI Identification Number:

00240

Antigen Name:

Jun Proto-Oncogene Peptide 2

CPTC Name:

CPTC-JUN Peptide 2

Keywords:

V-Jun Avian Sarcoma Virus 17 Oncogene Homolog; JUN oncogene; Activator Protein 1; Proto-Oncogene C-Jun; AP1; p39; V-Jun Sarcoma Virus 17 Oncogene Homolog; AP-1; c-JUN; Enhancer-Binding Protein AP1; Jun Activation Domain Binding Protein; Transcription Factot AP-1;

Function:

This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.

JUN (jun proto-oncogene) is a protein-coding gene. Diseases associated with JUN include sarcoma, and campylobacteriosis. GO annotations related to this gene include transcription coactivator activity and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is JUND.

Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.

Chromosomal Localization:

1p32-p31

Expression System:

NCBI Accession Number:

NP_002219.1

Swiss Prot Accession Number:

P05412

DNA Source:

N/A

Immunogen:

Synthetic Peptide

Vector Name:

N/A

Extinction Coefficient:

Buffers:

Expressed Sequence:

EEPQTVPEMPGETPPLS(ph)PIDMESQER (pS243)

Native Sequence:

Calculated Isoelectric Point:

0

Molecular Weight:

2860

Last Updated:

03/08/2018

Links

Characterization Data

SOPs

No SOPs available.

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