Ezrin Peptide 1
Rabbit Monoclonal Antibody
Peptide, Recombinant Full-length
This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org)
Indirect peptide ELISA (ie, binding of Antibody to biotinylated peptide coated on a NeutrAvidin plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.
Western Blot using CPTC-EZRIN-2 as primary Ab against full-length recombinant Ag 10474 (lane 2). Also included are molecular wt. standards (lane 1) and the EZRIN-2 Ab as positive control (lane 3).
NCI Identification Number:
Ezrin Peptide 1
CPTC-Ezrin Peptide 1
EZR; VIL2; Villin 2 (Ezrin); CVL; P81; CVIL; Cytovillin 2; Villin-2; Cytovillin
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.
Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial
cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis
UniProt Accession Number:
Calculated Isoelectric Point:
No SOPs available.
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