Background
Catalog Number:
CPTC-CXCL9-1
RRID:
AB_2617243
Target Antigen:
C-X-C Motif Chemokine Ligand 9
Isotype:
IgG2b
Species:
Mouse Monoclonal Antibody
Last Updated:
08/25/2021
Antigen Recognition(s):
Recombinant Full-length
Purchase
- DSHB CPTC-CXCL9-1
Characterization Data [Compare Characterization Data]
IHC HPA
CPTC-CXCL9-1 Evaluation by the Human Protein Atlas
Result: Negative
Results provided by the Human Protein Atlas (www.proteinatlas.org)
Characterization SOP Files
IHC NCI60
CPTC-CXCL9-1 IHC NCI60
Result: Negative
This antibody is not suitable for use in an Immunohistochemistry format as described in SOP M-106.
Characterization SOP Files
IHC Tissue
CPTC-CXCL9-1 IHC Tissue
Result: Negative
This antibody is not suitable for use in an Immunohistochemistry format as described in SOP M-106.
Characterization SOP Files
Indirect ELISA
CPTC-CXCL9-1 Indirect ELISA
Result: Positive
Indirect ELISA (ie, binding of Antibody to Antigen coated plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.
Characterization SOP Files
NCI 60 Protein Array
CPTC-CXCL9-1 NCI 60 Protein Array
Result: Negative
This antibody is not suitable for use in a Reverse Phase Protein Array format as described in SOP M-105.
Characterization SOP Files
Western Blot - Recombinant Protein or Peptide
CPTC-CXCL9-1 Western blot
Result: Positive
Western Blot using CPTC-CXCL9-1 as primary Ab against CXCL9 (rAg 11056) in lane 2. Also included are molecular wt. standards (lane 1) and mouse IgG control (lane 3).
Characterization SOP Files
Background
NCI Identification Number:
11056
Antigen Name:
C-X-C Motif Chemokine Ligand 9
CPTC Name:
CPTC-CXCL9
Aliases:
chemokine (C-X-C motif) ligand 9; C-X-C Motif Chemokine Ligand 9; SCYB9; Monokine Induced By Gamma Interferon; Monokine Induced By Interferon-Gamma; Gamma-Interferon-Induced Monokine; Chemokine (C-X-C Motif) Ligand 9; Small-Inducible Cytokine B9; C-X-C Motif Chemokine 9; Crg-10; CMK; MIG; CXCL9; HuMIG
Function:
This antimicrobial gene encodes a protein thought to be involved in T cell trafficking. The encoded protein binds to C-X-C motif chemokine 3 and is a chemoattractant for lymphocytes but not for neutrophils. CXCL9 (C-X-C Motif Chemokine Ligand 9) is a Protein Coding gene. Diseases associated with CXCL9 include Proliferative Glomerulonephritis and Paracoccidioidomycosis. Among its related pathways are Signaling by GPCR and PEDF Induced Signaling. Gene Ontology (GO) annotations related to this gene include cytokine activity and CXCR3 chemokine receptor binding. An important paralog of this gene is CXCL10.Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3.
Chromosomal Localization:
4q21.1
Expression System:
E. Coli
Accession Number:
BC063122.1
UniProt Accession Number:
Q07325
DNA Source:
OpenBiosystems - MHS1011-9199261
Immunogen:
Recombinant Full Length Protein
Vector Name:
pMCSG7
Extinction Coefficient:
5625
Buffers:
PBS without Ca++ and Mg++
Expressed Sequence:
SNATPVVRKGRCSCISTNQGTIHLQSLKDLKQFAPSPSCEKIEIIATLKN
GVQTCLNPDSADVKELIKKWEKQVSQKKKQKNGKKHQKKKVLKVRKSQRS
RQKKTT
Native Sequence:
MKKSGVLFLLGIILLVLIGVQGTPVVRKGRCSCISTNQGTIHLQSLKDLK
QFAPSPSCEKIEIIATLKNGVQTCLNPDSADVKELIKKWEKQVSQKKKQK
NGKKHQKKKVLKVRKSQRSRQKKTT
Calculated Isoelectric Point:
10.34
Molecular Weight:
11997
Last Updated:
09/02/2020
Links
- EnsEMBL - EnsEMBL CXCL9
- Entrez - Entrez CXCL9
- Uniprot - Uniprot Q07325
Characterization Data
Gel
Click image to enlarge
CPTC-CXCL9 PAGE
PAGE of CXCL9 (rAg 11056) with molecular weight standards in lane 1
Characterization SOP Files
SOPs
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