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Cellular Retinoic Acid Binding Protein 2 Peptide 1

Antibody: CPTC-CRABP2-1
Background

Catalog Number:

CPTC-CRABP2-1

Target Antigen:

Cellular Retinoic Acid Binding Protein 2 Peptide 1

Isotype:

IgG

Species:

Rabbit Recombinant Cloned Antibody

Last Updated:

03/20/2025

Antigen Recognition(s):

Peptide, Endogenous

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Characterization Data [Compare Characterization Data]
  IHC HPA
Download This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org) (398.6 KB)

CPTC-CRABP2-1 IHC evaluation by the Human Protein Atlas

Result: Negative

This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org)


Characterization SOP Files

  IHC Tissue
Click to enlarge image Tissue Micro-Array (TMA) core of breast showing cytoplasmic staining using Antibody CPTC-CRABP2-1. Titer: 1:1000 Click image to enlarge

CPTC-CRABP2-1 IHC Tissue

Result: Uncertain

Tissue Micro-Array (TMA) core of breast showing cytoplasmic staining using Antibody CPTC-CRABP2-1. Titer: 1:1000


Characterization SOP Files

  Immuno-MRM
Click to enlarge image iMRM screening of CPTC-CRABP2-1 against synthetic peptide SENFEELLK (Cellular Retinoic Acid Binding Protein 2 Peptide 1) Data provided by the Carr Lab, Broad Institute https://www.broadinstitute.org/proteomics/protocols Click image to enlarge

CPTC-CRABP2-1 iMRM screening (synthetic peptide)

Result: Positive

iMRM screening of CPTC-CRABP2-1 against synthetic peptide SENFEELLK (Cellular Retinoic Acid Binding Protein 2 Peptide 1)

Data provided by the Carr Lab, Broad Institute
https://www.broadinstitute.org/proteomics/protocols


Characterization SOP Files

  NCI 60 Protein Array
Click to enlarge image Protein Array in which CPTC-CRABP2-1 is screened against the NCI60 cell line panel for expression. Data is normalized to a mean signal of 1.0 and standard deviation of 0.5. Color conveys over-expression level (green), basal level (blue), under-expression level (red). Click image to enlarge

CPTC-CRABP2-1 NCI 60 Protein Array

Result: Positive

Protein Array in which CPTC-CRABP2-1 is screened against the NCI60 cell line panel for expression. Data is normalized to a mean signal of 1.0 and standard deviation of 0.5. Color conveys over-expression level (green), basal level (blue), under-expression level (red).


Characterization SOP Files

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Antigen: Cellular Retinoic Acid Binding Protein 2 Peptide 1
Background

NCI Identification Number:

00322

Antigen Name:

Cellular Retinoic Acid Binding Protein 2 Peptide 1

CPTC Name:

CPTC-CRABP2 Peptide 1

Aliases:

Cellular Retinoic Acid Binding Protein 2; CRABP-II; Cellular Retinoic Acid-Binding Protein II; CRABP2; RBP6

Function:

This gene encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. The protein is a cytosol-to-nuclear shuttling protein, which facilitates RA binding to its cognate receptor complex and transfer to the nucleus. It is involved in the retinoid signaling pathway, and is associated with increased circulating low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding the same protein have been found for this gene.CRABP2 (Cellular Retinoic Acid Binding Protein 2) is a Protein Coding gene. Diseases associated with CRABP2 include Embryonal Carcinoma and Hyperlipidemia, Familial Combined, 3. Among its related pathways are Signaling by GPCR and all-trans-Retinoic Acid Mediated Apoptosis. Gene Ontology (GO) annotations related to this gene include transporter activity and retinol binding. An important paralog of this gene is CRABP1.Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.

Chromosomal Localization:

1q23.1

Accession Number:

NP_001186652.1

UniProt Accession Number:

P29373

DNA Source:

N/A

Immunogen:

Synthetic Peptide

Vector Name:

N/A

Extinction Coefficient:

Buffers:

Expressed Sequence:

SENFEELLK

Native Sequence:

Calculated Isoelectric Point:

Molecular Weight:

990

Last Updated:

08/21/2020

Links

Characterization Data

SOPs

No SOPs available.

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