Background
Catalog Number:
CPTC-CRABP2-1
Target Antigen:
Cellular Retinoic Acid Binding Protein 2 Peptide 1
Isotype:
IgG
Species:
Rabbit Recombinant Cloned Antibody
Last Updated:
02/02/2024
Antigen Recognition(s):
Peptide, Endogenous
Purchase
- DSHB CPTC-CRABP2-1
Characterization Data [Compare Characterization Data]
IHC HPA
Download This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org) (398.6 KB)
CPTC-CRABP2-1 Evaluation by the Human Protein Atlas
Result: Negative
This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org)
Characterization SOP Files
IHC Tissue
CPTC-CRABP2-1 IHC Tissue
Result: Presumed Positive
Tissue Micro-Array (TMA) core of breast showing cytoplasmic staining using Antibody CPTC-CRABP2-1. Titer: 1:1000
Characterization SOP Files
Immuno-MRM
CPTC-CRABP2-1 iMRM screening (synthetic peptide)
Result: Positive
iMRM screening of CPTC-CRABP2-1 against synthetic peptide SENFEELLK (Cellular Retinoic Acid Binding Protein 2 Peptide 1)
Data provided by the Carr Lab, Broad Institute
https://www.broadinstitute.org/proteomics/protocols
Characterization SOP Files
NCI 60 Protein Array
CPTC-CRABP2-1 NCI 60 Protein Array
Result: Positive
Protein Array in which CPTC-CRABP2-1 is screened against the NCI60 cell line panel for expression. Data is normalized to a mean signal of 1.0 and standard deviation of 0.5. Color conveys over-expression level (green), basal level (blue), under-expression level (red).
Characterization SOP Files
Background
NCI Identification Number:
00322
Antigen Name:
Cellular Retinoic Acid Binding Protein 2 Peptide 1
CPTC Name:
CPTC-CRABP2 Peptide 1
Aliases:
Cellular Retinoic Acid Binding Protein 2; CRABP-II; Cellular Retinoic Acid-Binding Protein II; CRABP2; RBP6
Function:
This gene encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. The protein is a cytosol-to-nuclear shuttling protein, which facilitates RA binding to its cognate receptor complex and transfer to the nucleus. It is involved in the retinoid signaling pathway, and is associated with increased circulating low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding the same protein have been found for this gene.CRABP2 (Cellular Retinoic Acid Binding Protein 2) is a Protein Coding gene. Diseases associated with CRABP2 include Embryonal Carcinoma and Hyperlipidemia, Familial Combined, 3. Among its related pathways are Signaling by GPCR and all-trans-Retinoic Acid Mediated Apoptosis. Gene Ontology (GO) annotations related to this gene include transporter activity and retinol binding. An important paralog of this gene is CRABP1.Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.
Chromosomal Localization:
1q23.1
Accession Number:
NP_001186652.1
UniProt Accession Number:
P29373
DNA Source:
N/A
Immunogen:
Synthetic Peptide
Vector Name:
N/A
Extinction Coefficient:
Buffers:
Expressed Sequence:
SENFEELLK
Native Sequence:
Calculated Isoelectric Point:
Molecular Weight:
990
Last Updated:
08/21/2020
Links
- EnsEMBL - EnsEMBL CRABP2
- Entrez - Entrez CRABP2
- Uniprot - Uniprot P29373
Characterization Data
SOPs
No SOPs available.
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