Catalog Number:
CPTC-C17orf70-1
Target Antigen:
Chromosome 17 Open Reading Frame 70 Peptide 1
Isotype:
IgG
Species:
Rabbit Monoclonal Antibody
Last Updated:
03/08/2018
Antigen Recognition(s):
Peptide, Phosphorylation
Catalog Number:
CPTC-C17orf70-2
Target Antigen:
Chromosome 17 Open Reading Frame 70 Peptide 1
Isotype:
IgG
Species:
Rabbit Monoclonal Antibody
Last Updated:
03/08/2018
Antigen Recognition(s):
Peptide, Phosphorylation
NCI Identification Number:
00103
Antigen Name:
Chromosome 17 Open Reading Frame 70 Peptide 1
CPTC Name:
CPTC-C17orf70 Peptide 1
Aliases:
FAAP100; 100 kDa; Fanconi Anemia-Associated Protein; Fanconi Anemia Associated Protein 100 KDa Subunit; Fanconi Anemia Core Complex 100 KDa Subunit; Fanconi Anemia-Associated Protein Of 100 KDa; Fanconi Anemia-Associated Protein, 100kDa
Function:
FAAP100 is a component of the Fanconi anemia (FA; MIM 277650) core complex and is required for core complex stability and FANCD2 monoubiquitination.
C17orf70 (chromosome 17 open reading frame 70) is a protein-coding gene. Diseases associated with C17orf70 include fanconi's anemia, and fanconi anemia, complementation group m.
Plays a role in Fanconi anemia-associated DNA damage response network. Regulates FANCD2 monoubiquitination and the stability of the FA core complex. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed.
Chromosomal Localization:
17q25.3
Accession Number:
NP_079437.5
UniProt Accession Number:
Q0VG06
DNA Source:
N/A
Immunogen:
Synthetic Peptide
Vector Name:
N/A
Extinction Coefficient:
Buffers:
Expressed Sequence:
AP(pS)PLGPTR (pS667)
Native Sequence:
Calculated Isoelectric Point:
0
Molecular Weight:
990
Last Updated:
03/11/2015
No SOPs available.
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