Chromosome 17 Open Reading Frame 70 Peptide 1


Background

Catalog Number:

CPTC-C17orf70-1

Target Antigen:

Chromosome 17 Open Reading Frame 70 Peptide 1

Isotype:

IgG

Species:

Rabbit Monoclonal Antibody

Last Updated:

03/08/2018

Antigen Recognition(s):

Peptide, Phosphorylation

SOP:

Background

Catalog Number:

CPTC-C17orf70-2

Target Antigen:

Chromosome 17 Open Reading Frame 70 Peptide 1

Isotype:

IgG

Species:

Rabbit Monoclonal Antibody

Last Updated:

03/08/2018

Antigen Recognition(s):

Peptide, Phosphorylation

SOP:

Background

NCI Identification Number:

00103

Antigen Name:

Chromosome 17 Open Reading Frame 70 Peptide 1

CPTC Name:

CPTC-C17orf70 Peptide 1

Keywords:

FAAP100; 100 kDa; Fanconi Anemia-Associated Protein; Fanconi Anemia Associated Protein 100 KDa Subunit; Fanconi Anemia Core Complex 100 KDa Subunit; Fanconi Anemia-Associated Protein Of 100 KDa; Fanconi Anemia-Associated Protein, 100kDa

Function:

FAAP100 is a component of the Fanconi anemia (FA; MIM 277650) core complex and is required for core complex stability and FANCD2 monoubiquitination.

C17orf70 (chromosome 17 open reading frame 70) is a protein-coding gene. Diseases associated with C17orf70 include fanconi's anemia, and fanconi anemia, complementation group m.

Plays a role in Fanconi anemia-associated DNA damage response network. Regulates FANCD2 monoubiquitination and the stability of the FA core complex. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed.

Chromosomal Localization:

17q25.3

NCBI Accession Number:

NP_079437.5

Swiss Prot Accession Number:

Q0VG06

DNA Source:

N/A

Immunogen:

Synthetic Peptide

Vector Name:

N/A

Extinction Coefficient:

Buffers:

Expressed Sequence:

AP(pS)PLGPTR (pS667)

Native Sequence:

Calculated Isoelectric Point:

0

Molecular Weight:

990

Last Updated:

11/26/2019

Links

Characterization Data

SOPs

No SOPs available.

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