Background
Catalog Number:
CPTC-ANXA1-4
RRID:
AB_2617223
Target Antigen:
Annexin A1 Peptide 1
Isotype:
IgG
Species:
Rabbit Monoclonal Antibody
Last Updated:
08/26/2022
Antigen Recognition(s):
Peptide
Thematic Panel(s):
Immuno-Oncology (IO)
External Links
- CPTAC Assay Portal CPTAC-696
Publications
- Integrated Proteogenomic Characterization across Major Histological Types of Pediatric Brain Cancer (PMID: 33242424)
- Targeted Mass Spectrometry Enables Multiplexed Quantification of Immunomodulatory Proteins in Clinical Biospecimens (PMID: 34858420)
Characterization Data [Compare Characterization Data]
Indirect ELISA
CPTC-ANXA1-1 peptide ELISA
Result: Positive
Indirect ELISA (ie, binding of Antibody to biotinylated peptide coated on a NeutrAvidin plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.
Characterization SOP Files
Western Blot - Recombinant Protein or Peptide
CPTC-ANXA1-4 Western Blot Recombinant Protein
Result: Negative
Western blot using CPTC-ANXA1-4 as primary antibody against human annexin A4 (ANXA4) recombinant protein (lane 2). Expected molecular weight - 35.9 kDa. Molecular weight standards are also included (lane 1).
Characterization SOP Files
Background
NCI Identification Number:
00022
Antigen Name:
Annexin A1 Peptide 1
CPTC Name:
CPTC-ANXA1 Peptide 1
Aliases:
ANXA1; ANX1; Annexin-1; Chromobindin-9; LPC1; p35; Calpactin II; Lipocortin I; Phospholipase A2 Inhibitory Protein; P35; Calpactin-2
Function:
Annexin I belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.
Chromosomal Localization:
9q12 - q21.2
Accession Number:
BC001275
UniProt Accession Number:
P04083
DNA Source:
N/a
Immunogen:
Synthetic Peptide
Vector Name:
N/A
Extinction Coefficient:
Buffers:
Expressed Sequence:
AAYLQETGKPLDETLK
Native Sequence:
Calculated Isoelectric Point:
0
Molecular Weight:
1760
Last Updated:
06/11/2013
Links
- EnsEMBL - EnsEMBL ANXA1
- Entrez - Entrez ANXA1
- Uniprot - Uniprot P04083
Characterization Data
SOPs
No SOPs available.
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