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Arginine Vasopressin Receptor 1A Peptide 1

Antibody: CPTC-AVPR1A-1
Background

Catalog Number:

CPTC-AVPR1A-1

Target Antigen:

Arginine Vasopressin Receptor 1A Peptide 1

Isotype:

IgG

Species:

Rabbit Monoclonal Antibody

Last Updated:

02/09/2024

Antigen Recognition(s):

Peptide

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Characterization Data [Compare Characterization Data]
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Antigen: Arginine Vasopressin Receptor 1A Peptide 1
Background

NCI Identification Number:

00541

Antigen Name:

Arginine Vasopressin Receptor 1A Peptide 1

CPTC Name:

CPTC-AVPR1A Peptide 1

Aliases:

AVPR1A; Vascular/Hepatic-Type Arginine Vasopressin Receptor; Vasopressin V1a Receptor; AVPR V1a; V1aR; V1-Vascular Vasopressin Receptor AVPR1A; SCCL Vasopressin Subtype 1a Receptor; Antidiuretic Hormone Receptor 1A; Antidiuretic Hormone Receptor 1a; V1a Vasopressin Receptor

Function:

The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. AVPR1A (Arginine Vasopressin Receptor 1A) is a Protein Coding gene. Diseases associated with AVPR1A include Amusia and Hepatorenal Syndrome. Among its related pathways are Class A/1 (Rhodopsin-like receptors) and GPCR downstream signalling. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and protein kinase C binding. An important paralog of this gene is AVPR1B.Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment.Vasopressin receptors are a group of G-protein-coupled receptors that mediate vasoconstriction, antidiuresis and ACTH release. They are currently divided into three subtypes, V1A, V1B and V2 and are closely related to oxytocin receptors (OT).

Chromosomal Localization:

12q14.2

Accession Number:

NP_000697.1

UniProt Accession Number:

P37288

DNA Source:

N/A

Immunogen:

Synthetic Peptide

Vector Name:

N/A

Extinction Coefficient:

Buffers:

Expressed Sequence:

MRLSAGPDAGPSGC

Native Sequence:

Calculated Isoelectric Point:

Molecular Weight:

190

Last Updated:

03/13/2023

Links

Characterization Data

SOPs

No SOPs available.

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