A Service of the National Cancer Institute
Site by The Advanced Biomedical Computing Center (ABCC)
Tranche, an open source file sharing tool for scientific data, is the primary repository for proteomics data. Tranche allows collaborators to share research data regardless of file size, the number of files, or the file format. Tranche can also securely share data in pre-review before publication. Files can be encrypted and the passphrase is only available to the original uploader and whomever they share it with. In this way researchers can work at various locations and share data without worry about the security of the data being compromised. As such, Tranche is well-suited to serve as a data repository for mass spectrometry raw files.
Tranche has served as the repository for the CPTAC network, hosting all inter-laboratory data and metadata. Tranche and its associated annotation tool are in the process of becoming caBIG™ compliant, making CPTC data accessible to the broader biomedical research community.
Within the purview of technology assessment, CPTAC has made available a number of reference datasets. All of these datasets contain measurements of well-defined samples as well as technical replicates within a lab. Identical samples were also analyzed between labs, providing an assessment of inter-laboratory reproducibility. Descriptions of the available datasets are available on Tranche:
The Mouse Proteomic Technologies Initiative (MPTI) collected tissue and serum measurements from mouse models of different types of cancers using analytical techniques such as Mass Spectrometry. Nearly 1 terabyte of MPTI raw data has been deposited into Tranche and is shared with the scientific community.
A Service of the National Cancer Institute
Site by The Advanced Biomedical Computing Center (ABCC)
