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Thyroid Stimulating Hormone, beta Peptide 2

Antibody: CPTC-TSHB-2
Background

Catalog Number:

CPTC-TSHB-2

RRID:

AB_2617359

Target Antigen:

Thyroid Stimulating Hormone, beta Peptide 2

Isotype:

IgG

Species:

Rabbit Monoclonal Antibody

Last Updated:

09/27/2024

Antigen Recognition(s):

Peptide, Endogenous

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Characterization Data [Compare Characterization Data]
  IHC HPA
Download This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org) (307.6 KB)

CPTC-TSHB-2 Evaluation by the Human Protein Atlas

Result: Positive

This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org)


Characterization SOP Files

  Immuno-MRM
Click to enlarge image Immuno-MRM chromatogram of CPTC-TSHB-2 antibody (see CPTAC assay portal for details: https://assays.cancer.gov/CPTAC-691) Data provided by the Paulovich Lab, Fred Hutch (https://research.fredhutch.org/paulovich/en.html) Click image to enlarge

CPTC-TSHB-2 iMRM

Result: Positive

Immuno-MRM chromatogram of CPTC-TSHB-2 antibody (see CPTAC assay portal for details: https://assays.cancer.gov/CPTAC-691)

Data provided by the Paulovich Lab, Fred Hutch (https://research.fredhutch.org/paulovich/en.html)


Characterization SOP Files

  Immunofluorescence - HPA
Download This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org) (307.6 KB)

CPTC-TSHB-2 Evaluation by the Human Protein Atlas

Result: Negative

This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org)


Characterization SOP Files

  Indirect ELISA
Click to enlarge image Indirect ELISA (ie, binding of Antibody to biotinylated peptide coated on a NeutrAvidin plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding. Click image to enlarge

CPTC-TSHB-2 peptide ELISA

Result: Positive

Indirect ELISA (ie, binding of Antibody to biotinylated peptide coated on a NeutrAvidin plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.


Characterization SOP Files

  NCI 60 Protein Array

CPTC-TSHB-2 NCI 60 Protein Array

Result: Negative

This antibody is not suitable for use in a Reverse Phase Protein Array format as described in SOP M-105.


Characterization SOP Files

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Antigen: Thyroid Stimulating Hormone, beta Peptide 2
Background

NCI Identification Number:

00062

Antigen Name:

Thyroid Stimulating Hormone, beta Peptide 2

CPTC Name:

CPTC-TSHB Peptide 2

Aliases:

Thyroid Stimulating Hormone, Beta; Thyroid-Stimulating Hormone Subunit Beta; Thyrotropin Beta Chain; TSH-B; Thyrotropin Beta Subunit; TSH-BETA; Thyrotropin Subunit Beta; Thyrotropin Alfa; CHNG4

Function:

The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene result in congenital hypothyroidism.

Indispensable for the control of thyroid structure and metabolism.

Chromosomal Localization:

1p13

Accession Number:

NP_000540.2

UniProt Accession Number:

P01222

DNA Source:

N/A

Immunogen:

Synthetic Peptide

Vector Name:

N/A

Extinction Coefficient:

Buffers:

Expressed Sequence:

SYLVGFSV

Native Sequence:

Calculated Isoelectric Point:

0

Molecular Weight:

880

Last Updated:

10/30/2013

Links

Characterization Data

SOPs

No SOPs available.

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