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Ribonucleotide Reductase M2 Peptide 2

Antibody: CPTC-RRM2-2
Background

Catalog Number:

CPTC-RRM2-2

RRID:

AB_2617334

Target Antigen:

Ribonucleotide Reductase M2 Peptide 2

Isotype:

IgG

Species:

Rabbit Monoclonal Antibody

Last Updated:

02/09/2024

Antigen Recognition(s):

Peptide, Recombinant Full-length

Thematic Panel(s):

DNA Damage Response (DDR) Pathway

External Links
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Characterization Data [Compare Characterization Data]
  IHC HPA
Download This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org) (331.1 KB)

CPTC-RRM2-2 Evaluation by the Human Protein Atlas

Result: Negative

This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org)


Characterization SOP Files

  Indirect ELISA
Click to enlarge image Indirect ELISA (ie, binding of Antibody to biotinylated peptide coated on a NeutrAvidin plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding. Click image to enlarge

CPTC-RRM2-2 Indirect ELISA (peptide)

Result: Positive

Indirect ELISA (ie, binding of Antibody to biotinylated peptide coated on a NeutrAvidin plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.


Characterization SOP Files

  Indirect ELISA
Click to enlarge image Indirect ELISA (ie, binding of Antibody to full-length Antigen coated on plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding. Click image to enlarge

CPTC-RRM2-2 Indirect ELISA

Result: Positive

Indirect ELISA (ie, binding of Antibody to full-length Antigen coated on plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.


Characterization SOP Files

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Antigen: Ribonucleotide Reductase M2 Peptide 2
Background

NCI Identification Number:

00039

Antigen Name:

Ribonucleotide Reductase M2 Peptide 2

CPTC Name:

CPTC-RRM2 Peptide 2

Aliases:

Ribonucleotide Reductase M2 Polypeptide; Ribonucleotide Reductase Small Chain; Ribonucleotide Reductase Small Subunit; RR2; EC 1.17.4.1; R2; RR2M; Ribonucleoside-Diphosphate Reductase Subunit M2

Function:

This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the
formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a
cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1
and X.

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.

Chromosomal Localization:

2p25-p24

Accession Number:

NP_001025.1

UniProt Accession Number:

P31350

DNA Source:

N/A

Immunogen:

Synthetic Peptide

Vector Name:

N/A

Extinction Coefficient:

Buffers:

Expressed Sequence:

DIQHWESLKPEER

Native Sequence:

Calculated Isoelectric Point:

0

Molecular Weight:

1430

Last Updated:

06/21/2013

Links

Characterization Data

SOPs

No SOPs available.

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