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Nibrin Peptide 3

Antibody: CPTC-NBN-3
Background

Catalog Number:

CPTC-NBN-3

RRID:

AB_2888961

Target Antigen:

Nibrin Peptide 3

Isotype:

IgG

Species:

Rabbit Monoclonal Antibody

Last Updated:

01/04/2023

Antigen Recognition(s):

Peptide, Phosphorylation

Thematic Panel(s):

DNA Damage Response (DDR) Pathway

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Characterization Data [Compare Characterization Data]
  IHC HPA
Download This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org) (165.4 KB)

CPTC-NBN-3 Evaluation by the Human Protein Atlas

Result: Positive

This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org)


Characterization SOP Files

  Immuno-MRM
Click to enlarge image Immuno-MRM chromatogram of CPTC-NBN-3 antibody (see CPTAC assay portal for details: https://assays.cancer.gov/CPTAC-3239) Data provided by the Paulovich Lab, Fred Hutch (https://research.fredhutch.org/paulovich/en.html) Click image to enlarge

CPTC-NBN-3 iMRM

Result: Positive

Immuno-MRM chromatogram of CPTC-NBN-3 antibody (see CPTAC assay portal for details: https://assays.cancer.gov/CPTAC-3239)

Data provided by the Paulovich Lab, Fred Hutch (https://research.fredhutch.org/paulovich/en.html)


Characterization SOP Files

  Immunofluorescence - HPA
Click to enlarge image Results provided by the Human Protein Atlas (www.proteinatlas.org). The subcellular location is supported by literature. Immunofluorescent staining of human cell line THP-1 shows localization to nucleoplasm & mitotic chromosome. Human assay: THP-1 fixed with PFA, dilution: 1:100 Human assay: U2OS fixed with PFA, dilution: 1:100 Click image to enlarge

CPTC-NBN-3 Evaluation by the Human Protein Atlas

Result: Positive

Results provided by the Human Protein Atlas (www.proteinatlas.org). The subcellular location is supported by literature. Immunofluorescent staining of human cell line THP-1 shows localization to nucleoplasm & mitotic chromosome. Human assay: THP-1 fixed with PFA, dilution: 1:100
Human assay: U2OS fixed with PFA, dilution: 1:100


Characterization SOP Files

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Antigen: Nibrin Peptide 3
Background

NCI Identification Number:

00247

Antigen Name:

Nibrin Peptide 3

CPTC Name:

CPTC-NBN Peptide 3

Aliases:

NBS; NBS1; Nijmegen Breakage Syndrome 1; Cell Cycle Regulatory Protein P95; P95; At-V1; At-V2; ATV; P95 Protein Of The MRE11/RAD50 Complex; Nijmegen Breakage Syndrome Protein 1

Function:

Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer

Chromosomal Localization:

8q21

Accession Number:

XP_005250980.1

UniProt Accession Number:

O60934

DNA Source:

N/A

Immunogen:

Synthetic Peptide

Vector Name:

N/A

Extinction Coefficient:

Buffers:

Expressed Sequence:

IPNYQL(pS)PTK (pS432)

Native Sequence:

Calculated Isoelectric Point:

0

Molecular Weight:

1100

Last Updated:

09/01/2020

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Characterization Data

SOPs

No SOPs available.

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