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Chorionic Gonadotropin, beta polypeptide Peptide 1

Antibody: CPTC-CGB-1
Background

Catalog Number:

CPTC-CGB-1

RRID:

AB_2617232

Target Antigen:

Chorionic Gonadotropin, beta polypeptide Peptide 1

Isotype:

IgG

Species:

Rabbit Monoclonal Antibody

Last Updated:

09/05/2023

Antigen Recognition(s):

Peptide

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Characterization Data [Compare Characterization Data]
  Immuno-MRM
Click to enlarge image Immuno-MRM chromatogram of CPTC-CGB-1 antibody (see CPTAC assay portal for details: https://assays.cancer.gov/CPTAC-718) Data provided by the Paulovich Lab, Fred Hutch (https://research.fredhutch.org/paulovich/en.html) Click image to enlarge

CPTC-CGB-1 iMRM

Result: Positive

Immuno-MRM chromatogram of CPTC-CGB-1 antibody (see CPTAC assay portal for details: https://assays.cancer.gov/CPTAC-718)

Data provided by the Paulovich Lab, Fred Hutch (https://research.fredhutch.org/paulovich/en.html)


Characterization SOP Files

  Indirect ELISA
Click to enlarge image Indirect ELISA (ie, binding of Antibody to biotinylated peptide coated on a NeutrAvidin plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding. Click image to enlarge

CPTC-CGB-1 peptide ELISA

Result: Positive

Indirect ELISA (ie, binding of Antibody to biotinylated peptide coated on a NeutrAvidin plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.


Characterization SOP Files

  Western Blot - Recombinant Protein or Peptide

CPTC-CGB-1 recombinant protein WB

Result: Negative

Western blot using CPTC-CGB-1 as primary antibody against human chorionic gonadotropin beta chain
(hCG beta) recombinant protein. Data not shown.


Characterization SOP Files

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Antigen: Chorionic Gonadotropin, beta polypeptide Peptide 1
Background

NCI Identification Number:

00063

Antigen Name:

Chorionic Gonadotropin, beta polypeptide Peptide 1

CPTC Name:

CPTC-CGB Peptide 1

Aliases:

Chorionic Gonadotropin, Beta Polypeptide; CGB3; Chorionic Gonadotrophin Chain Beta; CG-Beta; CGB5; CGB7; CGB8; Choriogonadotropin Subunit Beta; Chorionic Gonadotropin Beta 3 Subunit; Chorionic Gonadotropin Beta Chain; Chorionic Gonadotropin Beta Subunit; HCGB

Function:

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates
the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is
encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene.

Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.

Chromosomal Localization:

19q13.32

Accession Number:

NP_000728.1

UniProt Accession Number:

P01233

DNA Source:

N/A

Immunogen:

Synthetic Peptide

Vector Name:

N/A

Extinction Coefficient:

Buffers:

Expressed Sequence:

VLQGVLPALPQVVCNYR

Native Sequence:

Calculated Isoelectric Point:

0

Molecular Weight:

1870

Last Updated:

09/15/2020

Links

Characterization Data

SOPs

No SOPs available.

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