Actin Group Peptide 1

CPTC-ACT Group-1

Actin Group Peptide 1

IgG

Rabbit Recombinant Cloned Antibody

02/26/2024

Peptide, Endogenous

00317

Actin Group Peptide 1

CPTC-ACT Group Peptide 1

Actin; ACTB; Actin Beta; Actin, Cytoplasmic 1; PS1TP5-Binding Protein 1; Beta Cytoskeletal Actin; I(2)-Actin; Beta-Actin; PS1TP5BP1; BRWS1; ACTA1; Actin Alpha 1, Skeletal Muscle; Actin, Alpha Skeletal Muscle; Nemaline Myopathy Type 3; Alpha-Actin-1; CFTD1; CFTDM; ASMA; CFTD; MPFD; NEM1; NEM2; NEM3; SHPM; ACTA2; Actin Alpha 2, Smooth Muscle; Cell Growth-Inhibiting Gene 46 Protein; Actin, Alpha 2, Smooth Muscle, Aorta; Actin, Aortic Smooth Muscle; ACTSA; Alpha-Cardiac Actin; Alpha-Actin-2; ACTVS; ACTG1; Actin Gamma 1; Actin, Cytoplasmic 2; ACTG; Deafness, Autosomal Dominant 20; Deafness, Autosomal Dominant 26; Epididymis Luminal Protein 176; Cytoskeletal Gamma-Actin; Gamma-Actin; HEL-176; DFNA20; DFNA26; ACTC1; Actin Alpha Cardiac Muscle 1; Actin, Alpha Cardiac Muscle 1; ACTC; Actin, Alpha, Cardiac Muscle; CMD1R; CMH11; LVNC4; ASD5; ACTG2; Actin Gamma 2, Smooth Muscle; Actin, Gamma 2, Smooth Muscle, Enteric; Actin, Gamma-Enteric Smooth Muscle; Alpha-Actin-3; ACTA3; ACTL3; ACTSG; Smooth Muscle Gamma-Actin; Actin-Like Protein; Gamma-2-Actin; ACTE; VSCM

A peptide homologous to a group of Actin proteins (Actin, ACTA2, ACTA1, ACTB, ACTG1 ACTC1 ACTG2) was used for antibody generation. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. ACTB: This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins that are ubiquitously expressed. Mutations in this gene cause Baraitser-Winter syndrome 1, which is characterized by intellectual disability with a distinctive facial appearance in human patients. Numerous pseudogenes of this gene have been identified throughout the human genome. ACTA1: The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause a variety of myopathies, including nemaline myopathy, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects with manifestations such as hypotonia. ACTA2: This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a smooth muscle actin that is involved in vascular contractility and blood pressure homeostasis. Mutations in this gene cause a variety of vascular diseases, such as thoracic aortic disease, coronary artery disease, stroke, and Moyamoya disease, as well as multisystemic smooth muscle dysfunction syndrome. ACTG1: Actins are highly conserved proteins that are involved in various types of cell motility and in maintenance of the cytoskeleton. Three main groups of actin isoforms have been identified in vertebrate animals: alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. Actin gamma 1, encoded by this gene, is a cytoplasmic actin found in all cell types. Mutations in this gene are associated with DFNA20/26, a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss and also with Baraitser-Winter syndrome. Alternative splicing results in multiple transcript variants. ACTC1: Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). ACTG2: ctins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Three types of actins, alpha, beta and gamma, have been identified in vertebrates. Alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. This gene encodes actin gamma 2; a smooth muscle actin found in enteric tissues. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Based on similarity to peptide cleavage of related actins, the mature protein of this gene is formed by removal of two N-terminal peptides.

ACTB - 7p22.1; ACTA1 - 1q42.13; ACTA2 - 10q23.31; ACTG1 - 17q25.3: ACTC1 - 15q14; ACTG2 - 2p13.1;

N/A

N/A

Synthetic Peptide

N/A

1320

06/16/2020