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Glutathione S-Transferase Pi 1 Peptide 1

Antibody: CPTC-GSTP1-1

Background

Catalog Number:
CPTC-GSTP1-1
Target Antigen:
Glutathione S-Transferase Pi 1 Peptide 1
Isotype:
IgG
Species:
Rabbit
Last Updated:
10/27/2014
Antigen Recognition(s):

Purchase

Characterization Data [Compare Characterization Data]

Indirect ELISA

Click to enlarge image Indirect ELISA (ie, binding of Antibody to Peptide coated plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.
Click to enlarge

CPTC-GSTP1-1 Indirect ELISA (peptide)

Indirect ELISA (ie, binding of Antibody to Peptide coated plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.

Characterization SOP Files

Antigen: Glutathione S-Transferase Pi 1 Peptide 1

Background

NCI Identification Number:
00028
Antigen Name:
Glutathione S-Transferase Pi 1 Peptide 1
CPTC Name:
CPTC-GSTP1 Peptide 1
Keywords:
GST3; FAEES3; GSTP; GSTP1-1; GST Class-Pi; EC 2.5.1.18; DFN7; PI; Deafness, X-Linked 7; Fatty Acid Ethyl Ester Synthase III; Glutathione S-Transferase P
Function:
Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.

Glutathione S-transferases (GSTs) are a family of enzymes that catalyze a variety of reactions in both eukaryotes and prokaryotes. They catalyze the conjugation of reduced glutathione with potentially toxic, xenobiotic substrates, thus aiding excretion from the body.

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.
Chromosomal Localization:
11q13.2
Expression System:
NCBI Accession Number:
AY324387.1
Swiss Prot Accession Number:
P09211
DNA Source:
N/A
Immunogen:
Synthetic Peptide
Vector Name:
N/A
Extinction Coefficient:
Buffers:
Expressed Sequence:
YISLIYTNYEAGK
Native Sequence:
Calculated Isoelectric Point:
0
Molecular Weight:
1430
Last Updated:
06/11/2013

Links

Characterization Data

SOPs

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