Catalog Number:
CPTC-XPNPEP1-1
RRID:
AB_2617378
Target Antigen:
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble Peptide 1
Isotype:
IgG
Species:
Rabbit Monoclonal Antibody
Last Updated:
02/09/2024
Antigen Recognition(s):
Peptide, Recombinant Full-length, Endogenous
Result: Positive
This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org)
Result: Positive
Indirect ELISA (ie, binding of Antibody to biotinylated peptide coated on a NeutrAvidin plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.
Result: Positive
Indirect ELISA (ie, binding of Antibody to full-length Antigen coated on plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.
Result: Positive
Western Blot using CPTC-XPNPEP-1 as primary Ab against HEK293T cell lysate containing XPNPEP (from Origene) in lane 2. Also included are molecular wt. standards (lane 1) and the XPNPEP-1 Ab as the IgG control (lane 3).
Result: Positive
Western Blot using CPTC-XPNPEP1-1 as primary Ab against lysates from six breast cancer cell lines from the NCI60 cell line collection (lanes 2-7). Also included are molecular wt. standards (lane 1).
NCI Identification Number:
00020
Antigen Name:
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble Peptide 1
CPTC Name:
CPTC-XPNPEP1 Peptide 1
Aliases:
X-Prolyl Aminopeptidase 1, Soluble; XPNPEPL; XPNPEPL1; XPNPEP; Aminoacylproline Aminopeptidase; Cytosolic Aminopeptidase P; Soluble Aminopeptidase P; X-Pro Aminopeptidase 1; EC 3.4.11.9; SAMP; X-Prolyl Aminopeptidase; (Aminopeptidase P)-Like; APP1; Aminopeptidase P, Cytosolic; Xaa-Pro Aminopeptidase 1; SAmp
Function:
This gene encodes the cytosolic form of a metalloaminopeptidase that catalyzes the cleavage of the N-terminal amino acid adjacent to a proline residue. The gene product may play a role in degradation and maturation of tachykinins, neuropeptides, and peptide hormones. Alternative splicing results in multiple transcript variants.
Contributes to the degradation of bradykinin. Catalyzes the removal of a penultimate prolyl residue from the
N-termini of peptides, such as Arg-Pro-Pro
Chromosomal Localization:
10q25.3
Accession Number:
NP_065116.3
UniProt Accession Number:
Q9NQw7
DNA Source:
N/A
Immunogen:
Synthetic Peptide
Vector Name:
N/A
Extinction Coefficient:
Buffers:
Expressed Sequence:
GSLTFEPLTLVPIQTK
Native Sequence:
Calculated Isoelectric Point:
0
Molecular Weight:
1760
Last Updated:
06/11/2013
No SOPs available.
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