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Transthyretin

Antibody: CPTC-TTR-1

Background

Catalog Number:
CPTC-TTR-1
Target Antigen:
Transthyretin
Isotype:
IgG2a
Species:
Mouse
Last Updated:
02/26/2013
Antigen Recognition(s):
recombinant full-length

Characterization Data [Compare Characterization Data]

Western Blot

Click to enlarge image Western Blot using CPTC-TTR-1 as primary Ab against TTR (Ag 11118) (lane 2). Also included are molecular wt. standards (lane 1) and mouse IgG control (lane 3).
Click to enlarge

CPTC-TTR-1 Western blot

Western Blot using CPTC-TTR-1 as primary Ab against TTR (Ag 11118) (lane 2). Also included are molecular wt. standards (lane 1) and mouse IgG control (lane 3).

Indirect ELISA

Click to enlarge image Indirect ELISA (ie, binding of Antibody to Antigen coated plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.
Click to enlarge

CPTC-TTR-1 Indirect ELISA

Indirect ELISA (ie, binding of Antibody to Antigen coated plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.

Characterization SOP Files

NCI 60 Protein Array

CPTC-TTR-1 NCI 60 Protein Array

This antibody is not suitable for use in a Reverse Phase Protein Array format as described in SOP M-105.

IHC NCI60

CPTC-TTR-1 IHC NCI60

This antibody is not suitable for use in an Immunohistochemistry format as described in SOP M-106.

Click to view IHC NCI60 Cell Line Array example

IHC Tissue

CPTC-TTR-1 IHC Tissue

This antibody is not suitable for use in an Immunohistochemistry format as described in SOP M-106.

Antigen: Transthyretin

Background

NCI Identification Number:
11118
Antigen Name:
Transthyretin
CPTC Name:
CPTC-TTR
Keywords:
Transthyretin; PALB; HsT2651; prealbumin, amyloidosis type 1; ATTR; TBPA; CTS; CTS1; carpal tunnel syndrome 1; thyroxine-binding prealbumin; prealbumin
Function:
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
Chromosomal Localization:
18q12.1
Expression System:
E. Coli
NCBI Accession Number:
BC005310
Swiss Prot Accession Number:
P02766
DNA Source:
HsCD00004170
Immunogen:
Recombinant Full Length Protein
Vector Name:
pMCSG7
Extinction Coefficient:
18450
Buffers:
PBS without Ca++ and Mg++
Expressed Sequence:
SNAPTGTGESKCPLMV
KVLDAVRGSPAINVAV
HVFRKAADDTWEPFAS
GKTSESGELHGLTTE
Native Sequence:
MASHRLLLLCLAGLVFVSEAGPTGTGESKC
PLMVKVLDAVRGSPAINVAVHVFRKAADDT
WEPFASGKTSESGELHGLTTEEEFVEGIYK
VEIDTKSYWKALGISPFHEHAEVVFTANDS
GPRRYTIAALLSPYSYSTTAVVTNPKE
Calculated Isoelectric Point:
5.35
Molecular Weight:
13704
Last Updated:
08/31/2012

Links

Characterization Data

Gel

Click to enlarge image Indirect ELISA (ie, binding of Antibody to Antigen coated plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.
Click to enlarge

CPTC-TTR PAGE

PAGE of TTR (rAg 11118) with molecular weight standards in lane 1

SOPs

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