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Transgelin Peptide 1

Antibody: CPTC-TAGLN-1

Background

Catalog Number:
CPTC-TAGLN-1
Target Antigen:
Transgelin Peptide 1
Isotype:
IgG
Species:
Rabbit
Last Updated:
04/02/2015
Antigen Recognition(s):
peptide, recombinant full-length, native protein

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Characterization Data [Compare Characterization Data]

Western Blot

Click to enlarge image Western Blot using CPTC-TAGLN-1 as primary Ab against full-length recombinant Ag 10361 (lane 2). Also included are molecular wt. standards (lane 1) and the TAGLN-1 Ab as positive control (lane 3).
Click to enlarge

CPTC-TAGLN-1 Western blot

Western Blot using CPTC-TAGLN-1 as primary Ab against full-length recombinant Ag 10361 (lane 2). Also included are molecular wt. standards (lane 1) and the TAGLN-1 Ab as positive control (lane 3).

Cell Lysate Western Blot

Click to enlarge image Western Blot using CPTC-TAGLN-1 as primary Ab against lysates from six breast cancer cell lines from the NCI60 cell line collection (lanes 2-7). Also included are molecular wt. standards (lane 1).
Click to enlarge

CPTC-TAGLN-1 NCI60 Western blot

Western Blot using CPTC-TAGLN-1 as primary Ab against lysates from six breast cancer cell lines from the NCI60 cell line collection (lanes 2-7). Also included are molecular wt. standards (lane 1).

Indirect ELISA

Click to enlarge image Indirect ELISA (ie, binding of Antibody to Peptide coated plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.
Click to enlarge

CPTC-TAGLN-1 Indirect ELISA (peptide)

Indirect ELISA (ie, binding of Antibody to Peptide coated plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.

Characterization SOP Files

Indirect ELISA

Click to enlarge image Indirect ELISA (ie, binding of Antibody to full-length Antigen coated on plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.
Click to enlarge

CPTC-TAGLN-1 Indirect ELISA

Indirect ELISA (ie, binding of Antibody to full-length Antigen coated on plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.

Antigen: Transgelin Peptide 1

Background

NCI Identification Number:
00042
Antigen Name:
Transgelin Peptide 1
CPTC Name:
CPTC-TAGLN Peptide 1
Keywords:
SM22; WS3-10; SMCC; TAGLN1; Smooth Muscle Protein 22-Alpha; 22 KDa Actin-Binding Protein; SM22-Alpha; DKFZp686P11128; Transgelin Variant 2; Protein WS3-10
Function:
The protein encoded by this gene is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear. Two transcript variants encoding the same protein have been found for this gene.

Actin cross-linking/gelling protein (By similarity). Involved in calcium interactions and contractile
properties of the cell that may contribute to replicative senescence.

Chromosomal Localization:
11q23.2
Expression System:
NCBI Accession Number:
NP_001001522.1
Swiss Prot Accession Number:
Q01995
DNA Source:
N/A
Immunogen:
Synthetic Peptide
Vector Name:
N/A
Extinction Coefficient:
Buffers:
Expressed Sequence:
AAEDYGVIK
Native Sequence:
Calculated Isoelectric Point:
0
Molecular Weight:
990
Last Updated:
06/21/2013

Links

Characterization Data

SOPs

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