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synuclein, gamma (breast cancer-specific protein 1) Peptide 1

Antibody: CPTC-SNCG-3
Background

Catalog Number:

CPTC-SNCG-3

RRID:

AB_2617346

Target Antigen:

synuclein, gamma (breast cancer-specific protein 1) Peptide 1

Isotype:

IgG

Species:

Rabbit Monoclonal Antibody

Last Updated:

02/09/2024

Antigen Recognition(s):

Peptide, Recombinant Full-length, Endogenous

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Characterization Data [Compare Characterization Data]
  IHC HPA
Download This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org) (400.8 KB)

CPTC-SNCG-3 Evaluation by the Human Protein Atlas

Result: Positive

This PDF contains the evaluation results provided by the Human Protein Atlas (www.proteinatlas.org)


Characterization SOP Files

  Indirect ELISA
Click to enlarge image Indirect ELISA (ie, binding of Antibody to full-length Antigen coated on plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding. Click image to enlarge

CPTC-SNCG-3 Indirect ELISA

Result: Positive

Indirect ELISA (ie, binding of Antibody to full-length Antigen coated on plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.


Characterization SOP Files

  Indirect ELISA
Click to enlarge image Indirect ELISA (ie, binding of Antibody to biotinylated peptide coated on a NeutrAvidin plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding. Click image to enlarge

CPTC-SNCG-3 peptide ELISA

Result: Positive

Indirect ELISA (ie, binding of Antibody to biotinylated peptide coated on a NeutrAvidin plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.


Characterization SOP Files

  Indirect ELISA
Click to enlarge image Indirect ELISA (ie, binding of Antibody to full-length Antigen coated on plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding. Click image to enlarge

CPTC-SNCG-3 Indirect ELISA

Result: Positive

Indirect ELISA (ie, binding of Antibody to full-length Antigen coated on plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.


Characterization SOP Files

  Western Blot - Recombinant Protein or Peptide
Click to enlarge image Western Blot using CPTC-SNCG-3 as primary Ab against full-length recombinant Ag 10504 (lane 2). Also included are molecular wt. standards (lane 1) and the SNCG-3 Ab as positive control (lane 3). Click image to enlarge

CPTC-SNCG-3 Western blot

Result: Positive

Western Blot using CPTC-SNCG-3 as primary Ab against full-length recombinant Ag 10504 (lane 2). Also included are molecular wt. standards (lane 1) and the SNCG-3 Ab as positive control (lane 3).


Characterization SOP Files

  Western Blot - Tissue or Cell Lysate
Click to enlarge image Western Blot using CPTC-SNCG-3 as primary Ab against lysates from six breast cancer cell lines from the NCI60 cell line collection (lanes 2-7). Also included are molecular wt. standards (lane 1). Click image to enlarge

CPTC-SNCG-3 NCI60 Western blot

Result: Positive

Western Blot using CPTC-SNCG-3 as primary Ab against lysates from six breast cancer cell lines from the NCI60 cell line collection (lanes 2-7). Also included are molecular wt. standards (lane 1).


Characterization SOP Files

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Antigen: synuclein, gamma (breast cancer-specific protein 1) Peptide 1
Background

NCI Identification Number:

00040

Antigen Name:

synuclein, gamma (breast cancer-specific protein 1) Peptide 1

CPTC Name:

CPTC-SNCG Peptide 1

Aliases:

BCSG1; SR; Persyn; Breast Cancer-Specific Gene 1 Protein; Gamma-Synuclein; Synoretin; PERSYN; PRSN

Function:

This gene encodes a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. Mutations in this gene have also been associated with breast tumor development.

Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during
development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway

Chromosomal Localization:

10q23.2-q23.3

Accession Number:

NP_003078.2

UniProt Accession Number:

O76070

DNA Source:

N/A

Immunogen:

Synthetic Peptide

Vector Name:

N/A

Extinction Coefficient:

Buffers:

Expressed Sequence:

TVEEAENIAVTSGVVR

Native Sequence:

Calculated Isoelectric Point:

0

Molecular Weight:

1760

Last Updated:

06/21/2013

Links

Characterization Data

SOPs

No SOPs available.

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