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synuclein-gamma

Antibody: CPTC-SNCG-1

Background

Catalog Number:
CPTC-SNCG-1
Target Antigen:
synuclein-gamma
Isotype:
IgG2a
Species:
Mouse
Last Updated:
02/26/2013
Antigen Recognition(s):
recombinant full-length

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External Links

Characterization Data [Compare Characterization Data]

Western Blot

Click to enlarge image Western Blot using CPTC-SNCG-1 as primary Ab against Ag 10504 (lane 2). Also included are molecular wt. standards (lane 1) and mouse IgG control (lane 3).
Click to enlarge

CPTC-SNCG-1 Western Blot

Western Blot using CPTC-SNCG-1 as primary Ab against Ag 10504 (lane 2). Also included are molecular wt. standards (lane 1) and mouse IgG control (lane 3).

Indirect ELISA

Click to enlarge image Indirect ELISA (ie, binding of Antibody to Antigen coated plate)
Click to enlarge

CPTC-SNCG-1 Indirect ELISA

Indirect ELISA (ie, binding of Antibody to Antigen coated plate)

Characterization SOP Files

NCI 60 Protein Array

CPTC-SNCG-1 NCI 60 Protein Array

This antibody is not suitable for use in a Reverse Phase Protein Array format as described in SOP M-105.

IHC NCI60

CPTC-SNCG-1 IHC NCI60

This antibody is not suitable for use in an Immunohistochemistry format as described in SOP M-106.

Click to view IHC NCI60 Cell Line Array example

IHC Tissue

CPTC-SNCG-1 IHC Tissue

This antibody is not suitable for use in an Immunohistochemistry format as described in SOP M-106.

Antibody: CPTC-SNCG-2

Background

Catalog Number:
CPTC-SNCG-2
Target Antigen:
synuclein-gamma
Isotype:
IgG2a
Species:
Mouse
Last Updated:
02/26/2013
Antigen Recognition(s):
recombinant full-length

Purchase

Characterization Data [Compare Characterization Data]

Western Blot

Click to enlarge image Western Blot using CPTC-SNCG-2 as primary Ab against Ag 10504 (lane 2). Also included are molecular wt. standards (lane 1) and mouse IgG control (lane 3).
Click to enlarge

CPTC-SNCG-2 Western Blot

Western Blot using CPTC-SNCG-2 as primary Ab against Ag 10504 (lane 2). Also included are molecular wt. standards (lane 1) and mouse IgG control (lane 3).

Indirect ELISA

Click to enlarge image Indirect ELISA (ie, binding of Antibody to Antigen coated plate)
Click to enlarge

CPTC-SNCG-2 Indirect ELISA

Indirect ELISA (ie, binding of Antibody to Antigen coated plate)

Characterization SOP Files

NCI 60 Protein Array

CPTC-SNCG-2 NCI 60 Protein Array

This antibody is not suitable for use in a Reverse Phase Protein Array format as described in SOP M-105.

IHC NCI60

CPTC-SNCG-2 IHC NCI60

This antibody is not suitable for use in an Immunohistochemistry format as described in SOP M-106.

Click to view IHC NCI60 Cell Line Array example

IHC Tissue

CPTC-SNCG-2 IHC Tissue

This antibody is not suitable for use in an Immunohistochemistry format as described in SOP M-106.

Antigen: synuclein-gamma

Background

NCI Identification Number:
10504
Antigen Name:
synuclein-gamma
CPTC Name:
CPTC-SNCG
Keywords:
SNCG; BCSG1; PERSYN; PRSN; SR; Synoretin; OTTHUMP00000020013
Function:
Synuclein-gamma is a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.

Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway (By similarity)
Chromosomal Localization:
10q23.2-q23.3
Expression System:
E. Coli
NCBI Accession Number:
BC014098
Swiss Prot Accession Number:
O76070
DNA Source:
HIP : HsCD00004878
Immunogen:
Recombinant Full Length Protein
Vector Name:
pMCSG7
Extinction Coefficient:
1490
Buffers:
50mM NH4HC03
Expressed Sequence:
SNAMDVFKKGFSIAKEGVVGAVEKTK
QGVTEAAEKTKEGVMYVGAKTKENVV
QSVTSVAEKTKEQANAVSEAVVSSVN
TVATKTVEEAENIAVTSGVVRKEDLR
PSAPQQEGEASKEKEEVAEEAQSGGD
Native Sequence:
MDVFKKGFSIAKEGVVGAVEKTKQGV
TEAAEKTKEGVMYVGAKTKENVVQSV
TSVAEKTKEQANAVSEAVVSSVNTVA
TKTVEEAENIAVTSGVVRKEDLRPSA
PQQEGEASKEKEEVAEEAQSGGD
Calculated Isoelectric Point:
4.89
Molecular Weight:
13603
Last Updated:
11/14/2012

Links

Characterization Data

Gel

Click to enlarge image Indirect ELISA (ie, binding of Antibody to Antigen coated plate)
Click to enlarge

CPTC-SNCG

PAGE of antigen CPTC-SNCG with molecular weight standards in Lane 1

SOPs

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