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Ribonucleotide Reductase M2 Peptide 2

Antibody: CPTC-RRM2-2

Background

Catalog Number:
CPTC-RRM2-2
Target Antigen:
Ribonucleotide Reductase M2 Peptide 2
Isotype:
IgG
Species:
Rabbit
Last Updated:
10/27/2014
Antigen Recognition(s):

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Characterization Data [Compare Characterization Data]

Indirect ELISA

Click to enlarge image Indirect ELISA (ie, binding of Antibody to biotinylated peptide coated on a NeutrAvidin plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.
Click to enlarge

CPTC-RRM2-2 Indirect ELISA (peptide)

Indirect ELISA (ie, binding of Antibody to biotinylated peptide coated on a NeutrAvidin plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.

Characterization SOP Files

Indirect ELISA

CPTC-RRM2-2 Indirect ELISA

Indirect ELISA (ie, binding of Antibody to full-length Antigen coated on plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.

Antigen: Ribonucleotide Reductase M2 Peptide 2

Background

NCI Identification Number:
00039
Antigen Name:
Ribonucleotide Reductase M2 Peptide 2
CPTC Name:
CPTC-RRM2 Peptide 2
Keywords:
Ribonucleotide Reductase M2 Polypeptide; Ribonucleotide Reductase Small Chain; Ribonucleotide Reductase Small Subunit; RR2; EC 1.17.4.1; R2; RR2M; Ribonucleoside-Diphosphate Reductase Subunit M2
Function:
This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the
formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a
cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1
and X.

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.

Chromosomal Localization:
2p25-p24
Expression System:
NCBI Accession Number:
NP_001025.1
Swiss Prot Accession Number:
P31350
DNA Source:
N/A
Immunogen:
Synthetic Peptide
Vector Name:
N/A
Extinction Coefficient:
Buffers:
Expressed Sequence:
DIQHWESLKPEER
Native Sequence:
Calculated Isoelectric Point:
0
Molecular Weight:
1430
Last Updated:
06/21/2013

Links

Characterization Data

SOPs

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