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Lectin, Galactoside-Binding, Soluble, 1 Peptide 1

Antibody: CPTC-LGALS1-1
Background

Catalog Number:

CPTC-LGALS1-1

RRID:

AB_2888957

Target Antigen:

Lectin, Galactoside-Binding, Soluble, 1 Peptide 1

Isotype:

IgG

Species:

Rabbit Monoclonal Antibody

Last Updated:

03/20/2024

Antigen Recognition(s):

Peptide, Endogenous

Thematic Panel(s):

Immuno-Oncology (IO)

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Characterization Data [Compare Characterization Data]
  IHC HPA
Download Results provided by the Human Protein Atlas (www.proteinatlas.org). (489.6 KB)

CPTC-LGALS1-1 evaluation by the Human Protein Atlas

Result: Negative

Results provided by the Human Protein Atlas (www.proteinatlas.org).


Characterization SOP Files

  Immuno-MRM
Click to enlarge image Immuno-MRM chromatogram of CPTC-LGALS1-1 antibody (see CPTAC assay portal for details: https://assays.cancer.gov/CPTAC-706) Data provided by the Paulovich Lab, Fred Hutch (https://research.fredhutch.org/paulovich/en.html). Data shown were obtained from plasmal. Data collected from FFPE tumor tissue lysate pool are available on the CPTAC assay portal (https://assays.cancer.gov/CPTAC-5947) Click image to enlarge

CPTC-LGALS1-1 iMRM

Result: Positive

Immuno-MRM chromatogram of CPTC-LGALS1-1 antibody (see CPTAC assay portal for details: https://assays.cancer.gov/CPTAC-706)
Data provided by the Paulovich Lab, Fred Hutch (https://research.fredhutch.org/paulovich/en.html). Data shown were obtained from plasmal. Data collected from FFPE tumor tissue lysate pool are available on the CPTAC assay portal (https://assays.cancer.gov/CPTAC-5947)


Characterization SOP Files

  Immunofluorescence - HPA
Download Results provided by the Human Protein Atlas (www.proteinatlas.org). (489.6 KB)

CPTC-LGALS1-1 evaluation by the Human Protein Atlas

Result: Negative

Results provided by the Human Protein Atlas (www.proteinatlas.org).


Characterization SOP Files

  Indirect ELISA
Click to enlarge image Indirect ELISA (ie, binding of Antibody to Peptide coated plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding. Click image to enlarge

CPTC-LGALS1-1 Indirect ELISA (peptide)

Result: Positive

Indirect ELISA (ie, binding of Antibody to Peptide coated plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.


Characterization SOP Files

  Western Blot - Recombinant Protein or Peptide

CPTC-LGALS1-1 Western Blot (Recombinant Protein)

Result: Negative

Western blot using CPTC-LGALS1-1 as primary antibody against human Galectin 1 (LGALS1) recombinant protein (lane 2). Molecular weight standards are also included (lane 1). Expected molecular weight – 14.5 kDa.


Characterization SOP Files

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Antigen: Lectin, Galactoside-Binding, Soluble, 1 Peptide 1
Background

NCI Identification Number:

00033

Antigen Name:

Lectin, Galactoside-Binding, Soluble, 1 Peptide 1

CPTC Name:

CPTC-LGALS1 Peptide 1

Aliases:

GBP; Beta-Galactoside-Binding Lectin L-14-I; Lactose-Binding Lectin 1; Putative MAPK-Activating Protein PM12; 14 KDa Laminin-Binding Protein; 14 KDa Lectin; HBL; HLBP14; HPL; S-Lac Lectin 1; GAL1; Beta-Galactoside-Binding Protein; 14kDa; Galaptin; Galectin-1; LGALS1

Function:

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This gene product may act as an autocrine negative growth factor that regulates cell proliferation.

May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase.

Chromosomal Localization:

22q13.l

Accession Number:

NP_002296.1

UniProt Accession Number:

P09382

DNA Source:

N/A

Immunogen:

Synthetic Peptide

Vector Name:

N/A

Extinction Coefficient:

Buffers:

Expressed Sequence:

SFVLNLGK

Native Sequence:

Calculated Isoelectric Point:

0

Molecular Weight:

880

Last Updated:

06/11/2013

Links

Characterization Data

SOPs

No SOPs available.

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