Heat Shock 27kDa Protein 1 Peptide 1


Background

Catalog Number:

CPTC-HSPB1-4

RRID:

AB_2617270

Target Antigen:

Heat Shock 27kDa Protein 1 Peptide 1

Isotype:

IgG

Species:

Rabbit Monoclonal Antibody

Last Updated:

03/20/2024

Antigen Recognition(s):

Peptide, Recombinant Full-length, Endogenous

External Links
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Characterization Data [Compare Characterization Data]
  IHC HPA
Download Results provided by the Human Protein Atlas (www.proteinatlas.org). (525.0 KB)

CPTC-HSPB1-4 evaluation by the Human Protein Atlas

Result: Negative

Results provided by the Human Protein Atlas (www.proteinatlas.org).


  Immuno-MRM
Click to enlarge image Immuno-MRM chromatogram of CPTC-HSPB1-4 antibody (see CPTAC assay portal for details: https://assays.cancer.gov/CPTAC-702)
Data provided by the Paulovich Lab, Fred Hutch (https://research.fredhutch.org/paulovich/en.html). Data shown were obtained from plasma. Click image to enlarge

CPTC-HSPB1-4 iMRM

Result: Positive

Immuno-MRM chromatogram of CPTC-HSPB1-4 antibody (see CPTAC assay portal for details: https://assays.cancer.gov/CPTAC-702)
Data provided by the Paulovich Lab, Fred Hutch (https://research.fredhutch.org/paulovich/en.html). Data shown were obtained from plasma.


  Immunofluorescence - HPA
Download Results provided by the Human Protein Atlas (www.proteinatlas.org). (525.0 KB)

CPTC-HSPB1-4 evaluation by the Human Protein Atlas

Result: Negative

Results provided by the Human Protein Atlas (www.proteinatlas.org).


  Indirect ELISA
Click to enlarge image Indirect ELISA (ie, binding of Antibody to biotinylated peptide coated on a NeutrAvidin plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding. Click image to enlarge

CPTC-HSPB1-4 peptide ELISA

Result: Positive

Indirect ELISA (ie, binding of Antibody to biotinylated peptide coated on a NeutrAvidin plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.


Characterization SOP Files

  Indirect ELISA
Click to enlarge image Indirect ELISA (ie, binding of Antibody to full-length Antigen coated on plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding. Click image to enlarge

CPTC-HSPB1-4 Indiect ELISA

Result: Positive

Indirect ELISA (ie, binding of Antibody to full-length Antigen coated on plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.


Background

NCI Identification Number:

00029

Antigen Name:

Heat Shock 27kDa Protein 1 Peptide 1

CPTC Name:

CPTC-HSPB1 Peptide 1

Aliases:

HSPB1; CMT2F; HMN2B; DKFZp586P1322; HS.76067; HSP27; HSP28; Hsp25; HspB1; OTTHUMP00000024846; SRP27

Function:

The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN).

Involved in stress resistance and actin organization

Chromosomal Localization:

7q11.23

Accession Number:

NM_001540

UniProt Accession Number:

P04792

DNA Source:

N/A

Immunogen:

Synthetic Peptide

Vector Name:

N/A

Extinction Coefficient:

Buffers:

Expressed Sequence:

DGVVEITGK

Native Sequence:

Calculated Isoelectric Point:

0

Molecular Weight:

880

Last Updated:

06/11/2013

Links

Characterization Data

SOPs

No SOPs available.

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