Chloride Intracellular Channel 1
Background
Purchase
- DSHB CPTC-CLIC1-1
External Links
- Human Protein Atlas CPTC-CLIC1-1
Characterization Data [Compare Characterization Data]
Western Blot
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CPTC-CLIC1-1 Western Blot
Western Blot using CPTC-CLIC1-1 as primary Ab against Ag 10458 (lane 2). Also included are molecular wt. standards (lane 1) and mouse IgG control (lane 3).
Characterization SOP Files
Indirect ELISA
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CPTC-CLIC1-1 Indirect ELISA
Indirect ELISA (ie, binding of Antibody to Antigen coated plate)
Characterization SOP Files
NCI 60 Protein Array
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CPTC-CLIC1-1 NCI60 Protein Array
Protein Array in which CPTC-CLIC1-1 is screened against the NCI60 cell line panel for expression. Data is normalized to a mean signal of 1.0 and standard deviation of 0.5. Color conveys over-expression level (green), basal level (blue), under-expression level (red).
Characterization SOP Files
IHC NCI60
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CPTC-CLIC1-1 IHC NCI60
Immuno-histochemistry of CPTC-CLIC1-1 for NCI60 Cell Line Array at titer 1:250
0=NEGATIVE
1=WEAK(red)
2=MODERATE(blue)
3=STRONG(green)
Characterization SOP Files
IHC Tissue
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CPTC-CLIC1-1 IHC Tissue
Tissue Micro-Array(TMA) core of ovarian cancer showing cytoplasmic staining using Antibody CPTC-CLIC1-1. Titer: 1:250
Characterization SOP Files
Background
Purchase
- DSHB CPTC-CLIC1-2
Characterization Data [Compare Characterization Data]
Western Blot
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CPTC-CLIC1-2 Western Blot
Western Blot using CPTC-CLIC1-2 as primary Ab against Ag 10458 (lane 2). Also included are molecular wt. standards (lane 1) and mouse IgG control (lane 3).
Characterization SOP Files
Indirect ELISA
Click to enlarge
CPTC-CLIC1-2 Indirect ELISA
Indirect ELISA (ie, binding of Antibody to Antigen coated plate)
Characterization SOP Files
NCI 60 Protein Array
Click to enlarge
CPTC-CLIC1-2 Protein Array
Protein Array in which CPTC-CLIC1-2 is screened against the NCI60 cell line panel for expression. Data is normalized to a mean signal of 1.0 and standard deviation of 0.5. Color conveys over-expression level (green), basal level (blue), under-expression level (red).
Characterization SOP Files
IHC NCI60
Click to enlarge
CPTC-CLIC1-2 IHC NCI60
Immunohistochemistry of CPTC-CLIC1-2 for NCI60 Cell Line Array. Data scored as:
0=NEGATIVE
1=WEAK (red)
2=MODERATE (blue)
3=STRONG (green)
Titer: 1:250
Characterization SOP Files
IHC Tissue
Click to enlarge
CPTC-CLIC1-2 IHC Tissue
Tissue Micro-Array(TMA) core of ovarian cancer showing cytoplasmic staining using Antibody CPTC-CLIC1-2. Titer: 1:250
Characterization SOP Files
Background
including stabilization of cell membrane potential,transepithelial transport, maintenance of
intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.
DTKRRTETVQKLCPGGQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPK
LAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDNYL
TSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKK
YRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKALK
RRTETVQKLCPGGQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAA
LNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDNYLTSP
LPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRG
FTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKALK
Links
- Uniprot - Uniprot CLIC1
- Entrez - Entrez CLIC1
Characterization Data
Gel
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CPTC-CLIC1 (rAg 10458) PAGE
PAGE of CLIC1 (rAg 10458) with molecular weight standards in lane 1.
SOPs
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